LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_1
 Taxol 72 0.0036 -0.2565 0.7506 0.00447 -0.2269 1.7041 0.9900
1.11022302463e-16
MCF10A-GM_8
 Neratinib 72 0.4944 0.1601 0.2140 0.38258 0.1735 1.6620 0.9455
1.25455201783e-14
MCF10A-GM_8
 Taxol 72 0.0041 -0.2560 0.7346 0.00512 -0.2260 1.6494 0.9902
1.11022302463e-16
MCF10A-GM_7
 Taxol 72 0.0037 -0.2470 0.7442 0.00467 -0.2327 1.6111 0.9916
1.11022302463e-16
MCF10A-GM_2
 Taxol 72 0.0034 -0.2221 0.7684 0.00420 -0.2170 1.6095 0.9928
1.11022302463e-16
MCF10A-GM_9
 Taxol 72 0.0037 -0.2442 0.7335 0.00470 -0.2263 1.6044 0.9924
1.11022302463e-16
MCF10A-GM_4
 Neratinib 72 0.3333 0.1249 0.2789 0.25439 0.1756 1.6016 0.8850
4.64310812021e-11
MCF10A-GM_4
 Taxol 72 0.0036 -0.2361 0.7531 0.00459 -0.2325 1.5776 0.9936
1.11022302463e-16
MCF10A-GM_3
 Taxol 72 0.0032 -0.2644 0.7716 0.00409 -0.2204 1.5590 0.9925
1.11022302463e-16
MCF10A-GM_7
 Neratinib 72 0.6343 0.1902 0.1983 0.47136 0.1837 1.5425 0.9280
2.69895217286e-13
MCF10A-GM_5
 Taxol 72 0.0035 -0.2405 0.7502 0.00450 -0.2273 1.5202 0.9935
1.11022302463e-16
MCF10A-GM_6
 Neratinib 72 0.3653 0.1217 0.2764 0.31106 0.1080 1.5128 0.9320
1.43329792479e-13
MCF10A-GM_6
 Taxol 72 0.0035 -0.2324 0.7521 0.00448 -0.2160 1.4996 0.9915
1.11022302463e-16
MCF10A-GM_1
 Etoposide 72 0.2323 0.0175 0.4818 0.23150 0.0024 1.4514 0.9879
1.11022302463e-16
MCF10A-GM_6
 Etoposide 72 0.2631 0.0338 0.4508 0.25611 0.0190 1.4355 0.9907
1.11022302463e-16
MCF10A-GM_5
 Neratinib 72 0.3531 0.1178 0.2790 0.30699 0.0908 1.4312 0.9264
3.44724249146e-13
MCF10A-GM_9
 Neratinib 72 0.5877 0.1245 0.2085 0.48257 0.1227 1.4294 0.9393
4.10782519111e-14
MCF10A-GM_8
 Etoposide 72 0.3062 0.0111 0.4362 0.30305 0.0072 1.4070 0.9958
1.11022302463e-16
MCF10A-GM_2
 Etoposide 72 0.2479 0.0064 0.4665 0.24608 0.0050 1.3936 0.9932
1.11022302463e-16
MCF10A-GM_9
 Etoposide 72 0.3309 0.0254 0.4307 0.33219 -0.0027 1.3774 0.9906
1.11022302463e-16
MCF10A-GM_7
 Etoposide 72 0.3042 0.0190 0.4408 0.30097 0.0071 1.3586 0.9944
1.11022302463e-16
MCF10A-GM_7
 Trametinib 72 0.0039 0.0719 0.6340 0.00325 0.1062 1.3464 0.9839
1.11022302463e-16
MCF10A-GM_5
 Vorinostat 72 1.3313 0.0338 0.2592 1.36448 -0.0168 1.3398 0.9902
1.11022302463e-16
MCF10A-GM_5
 Etoposide 72 0.2715 0.0390 0.4546 0.26956 0.0047 1.3382 0.9912
1.11022302463e-16
MCF10A-GM_2
 Neratinib 72 0.2054 0.0672 0.3563 0.18651 0.0602 1.3299 0.9097
3.26805249529e-12
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