LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)
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| Cell | Small Molecule | Timepoint | GR50 | GRmax | GR_AOC | GEC50 | GRinf | h_GR | r2_GR | pval_GR |
|---|---|---|---|---|---|---|---|---|---|---|
MCF10A-GM_3 | Taxol | 72 | 0.0032 | -0.2644 | 0.7716 | 0.00409 | -0.2204 | 1.5590 | 0.9925 | 1.11022302463e-16 |
MCF10A-GM_1 | Taxol | 72 | 0.0036 | -0.2565 | 0.7506 | 0.00447 | -0.2269 | 1.7041 | 0.9900 | 1.11022302463e-16 |
MCF10A-GM_8 | Taxol | 72 | 0.0041 | -0.2560 | 0.7346 | 0.00512 | -0.2260 | 1.6494 | 0.9902 | 1.11022302463e-16 |
MCF10A-GM_7 | Taxol | 72 | 0.0037 | -0.2470 | 0.7442 | 0.00467 | -0.2327 | 1.6111 | 0.9916 | 1.11022302463e-16 |
MCF10A-GM_9 | Taxol | 72 | 0.0037 | -0.2442 | 0.7335 | 0.00470 | -0.2263 | 1.6044 | 0.9924 | 1.11022302463e-16 |
MCF10A-GM_5 | Taxol | 72 | 0.0035 | -0.2405 | 0.7502 | 0.00450 | -0.2273 | 1.5202 | 0.9935 | 1.11022302463e-16 |
MCF10A-GM_4 | Taxol | 72 | 0.0036 | -0.2361 | 0.7531 | 0.00459 | -0.2325 | 1.5776 | 0.9936 | 1.11022302463e-16 |
MCF10A-GM_6 | Taxol | 72 | 0.0035 | -0.2324 | 0.7521 | 0.00448 | -0.2160 | 1.4996 | 0.9915 | 1.11022302463e-16 |
MCF10A-GM_2 | Taxol | 72 | 0.0034 | -0.2221 | 0.7684 | 0.00420 | -0.2170 | 1.6095 | 0.9928 | 1.11022302463e-16 |
MCF10A-GM_3 | Dasatinib | 72 | 0.3180 | -0.1962 | 0.4706 | 0.67309 | -0.3178 | 0.6561 | 0.9749 | 1.11022302463e-16 |
MCF10A-GM_5 | Dasatinib | 72 | 0.3227 | -0.1921 | 0.4426 | 0.48669 | -0.1945 | 0.7999 | 0.9614 | 3.33066907388e-16 |
MCF10A-GM_6 | Dasatinib | 72 | 0.3435 | -0.1607 | 0.4528 | 0.66326 | -0.2814 | 0.6786 | 0.9728 | 1.11022302463e-16 |
MCF10A-GM_8 | Dasatinib | 72 | 0.3362 | -0.1510 | 0.4405 | 0.46460 | -0.1541 | 0.8309 | 0.9643 | 1.11022302463e-16 |
MCF10A-GM_2 | Dasatinib | 72 | 0.3007 | -0.1486 | 0.4680 | 0.61942 | -0.3062 | 0.6611 | 0.9635 | 1.11022302463e-16 |
MCF10A-GM_4 | Dasatinib | 72 | 0.3273 | -0.1411 | 0.4382 | 0.51788 | -0.2003 | 0.7342 | 0.9688 | 1.11022302463e-16 |
MCF10A-GM_1 | Dasatinib | 72 | 0.2837 | -0.1309 | 0.4667 | 0.43854 | -0.2021 | 0.7795 | 0.9729 | 1.11022302463e-16 |
MCF10A-GM_9 | Dasatinib | 72 | 0.4467 | -0.1284 | 0.4150 | 0.83179 | -0.2801 | 0.7155 | 0.9765 | 1.11022302463e-16 |
MCF10A-GM_7 | Dasatinib | 72 | 0.3822 | -0.1253 | 0.4260 | 0.60000 | -0.2136 | 0.7889 | 0.9676 | 1.11022302463e-16 |
MCF10A-GM_7 | Vorinostat | 72 | 1.5485 | 0.0052 | 0.2515 | 1.79233 | -0.1001 | 1.2484 | 0.9918 | 1.11022302463e-16 |
MCF10A-GM_2 | Etoposide | 72 | 0.2479 | 0.0064 | 0.4665 | 0.24608 | 0.0050 | 1.3936 | 0.9932 | 1.11022302463e-16 |
MCF10A-GM_8 | Etoposide | 72 | 0.3062 | 0.0111 | 0.4362 | 0.30305 | 0.0072 | 1.4070 | 0.9958 | 1.11022302463e-16 |
MCF10A-GM_3 | Etoposide | 72 | 0.2400 | 0.0138 | 0.4788 | 0.24005 | -0.0002 | 1.2891 | 0.9909 | 1.11022302463e-16 |
MCF10A-GM_3 | Vorinostat | 72 | 1.1270 | 0.0140 | 0.2901 | 1.24865 | -0.0667 | 1.2227 | 0.9848 | 1.11022302463e-16 |
MCF10A-GM_2 | Vorinostat | 72 | 1.1217 | 0.0167 | 0.2934 | 1.30060 | -0.0891 | 1.1078 | 0.9862 | 1.11022302463e-16 |
MCF10A-GM_1 | Etoposide | 72 | 0.2323 | 0.0175 | 0.4818 | 0.23150 | 0.0024 | 1.4514 | 0.9879 | 1.11022302463e-16 |