LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_9
 Alpelisib 72 11.2837 0.4721 0.1219 77.89622 -1.0000 0.5686 0.9588
5.55111512313e-16
MCF10A-GM_8
 Alpelisib 72 10.0251 0.4477 0.1231 65.93350 -1.0000 0.5833 0.9758
1.11022302463e-16
MCF10A-GM_7
 Alpelisib 72 11.5543 0.4925 0.1271 7.97966 0.1098 0.6701 0.9498
5.10702591328e-15
MCF10A-GM_5
 Alpelisib 72 8.5470 0.4318 0.1327 54.70483 -1.0000 0.5918 0.9673
1.11022302463e-16
MCF10A-GM_6
 Alpelisib 72 9.3375 0.4071 0.1347 69.94454 -1.0000 0.5456 0.9466
9.99200722163e-15
MCF10A-GM_4
 Alpelisib 72 9.9368 0.4353 0.1434 78.91713 -1.0000 0.5302 0.9350
8.71525074331e-14
MCF10A-GM_3
 Alpelisib 72 7.4487 0.4036 0.1516 49.04215 -1.0000 0.5829 0.9653
1.11022302463e-16
MCF10A-GM_1
 Alpelisib 72 8.2016 0.4069 0.1540 65.49912 -1.0000 0.5288 0.9578
7.77156117238e-16
MCF10A-GM_2
 Alpelisib 72 7.3886 0.4254 0.1560 53.37110 -1.0000 0.5556 0.9629
2.22044604925e-16
MCF10A-GM_7
 Neratinib 72 0.6343 0.1902 0.1983 0.47136 0.1837 1.5425 0.9280
2.69895217286e-13
MCF10A-GM_9
 Neratinib 72 0.5877 0.1245 0.2085 0.48257 0.1227 1.4294 0.9393
4.10782519111e-14
MCF10A-GM_8
 Neratinib 72 0.4944 0.1601 0.2140 0.38258 0.1735 1.6620 0.9455
1.25455201783e-14
MCF10A-GM_9
 Palbociclib 72 1.5113 0.2927 0.2181 0.72834 0.2462 0.9291 0.9902
1.11022302463e-16
MCF10A-GM_8
 Palbociclib 72 1.3076 0.2218 0.2364 0.78812 0.1724 0.8353 0.9515
3.06659142524e-11
MCF10A-GM_9
 Vorinostat 72 1.5617 0.0388 0.2396 1.73350 -0.0679 1.2213 0.9929
1.11022302463e-16
MCF10A-GM_7
 Palbociclib 72 1.2911 0.1975 0.2446 0.98102 0.0926 0.7453 0.9668
1.48003831413e-12
MCF10A-GM_7
 Vorinostat 72 1.5485 0.0052 0.2515 1.79233 -0.1001 1.2484 0.9918
1.11022302463e-16
MCF10A-GM_6
 Palbociclib 72 1.4030 0.2080 0.2525 1.29780 0.0259 0.6833 0.9900
1.11022302463e-16
MCF10A-GM_8
 Vorinostat 72 1.4114 0.0224 0.2573 1.60992 -0.0799 1.1262 0.9912
1.11022302463e-16
MCF10A-GM_5
 Vorinostat 72 1.3313 0.0338 0.2592 1.36448 -0.0168 1.3398 0.9902
1.11022302463e-16
MCF10A-GM_6
 Vorinostat 72 1.3632 0.0467 0.2659 1.48443 -0.0521 1.1625 0.9892
1.11022302463e-16
MCF10A-GM_5
 Palbociclib 72 0.8421 0.1400 0.2682 0.57902 0.1419 0.8908 0.9852
2.22044604925e-15
MCF10A-GM_4
 Vorinostat 72 1.2988 0.0419 0.2685 1.40992 -0.0509 1.1821 0.9889
1.11022302463e-16
MCF10A-GM_4
 Palbociclib 72 1.0359 0.1030 0.2711 1.08666 -0.0193 0.7905 0.9851
2.44249065418e-15
MCF10A-GM_6
 Neratinib 72 0.3653 0.1217 0.2764 0.31106 0.1080 1.5128 0.9320
1.43329792479e-13
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