LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_2
 Trametinib 72 0.0031 0.0932 0.6454 0.00247 0.1261 1.2703 0.9864
1.11022302463e-16
MCF10A-GM_3
 Trametinib 72 0.0032 0.0891 0.6444 0.00254 0.1236 1.1674 0.9882
1.11022302463e-16
MCF10A-GM_4
 Trametinib 72 0.0035 0.0966 0.6434 0.00287 0.1094 1.2248 0.9799
1.11022302463e-16
MCF10A-GM_5
 Trametinib 72 0.0037 0.1008 0.6277 0.00294 0.1274 1.3150 0.9855
1.11022302463e-16
MCF10A-GM_1
 Trametinib 72 0.0037 0.0635 0.6324 0.00299 0.1133 1.2768 0.9809
1.11022302463e-16
MCF10A-GM_6
 Trametinib 72 0.0038 0.1052 0.6376 0.00301 0.1167 1.2006 0.9837
1.11022302463e-16
MCF10A-GM_9
 Trametinib 72 0.0038 0.0688 0.6336 0.00308 0.1142 1.3043 0.9848
1.11022302463e-16
MCF10A-GM_7
 Trametinib 72 0.0039 0.0719 0.6340 0.00325 0.1062 1.3464 0.9839
1.11022302463e-16
MCF10A-GM_8
 Trametinib 72 0.0040 0.1027 0.6263 0.00331 0.1110 1.2895 0.9906
1.11022302463e-16
MCF10A-GM_3
 Taxol 72 0.0032 -0.2644 0.7716 0.00409 -0.2204 1.5590 0.9925
1.11022302463e-16
MCF10A-GM_2
 Taxol 72 0.0034 -0.2221 0.7684 0.00420 -0.2170 1.6095 0.9928
1.11022302463e-16
MCF10A-GM_1
 Taxol 72 0.0036 -0.2565 0.7506 0.00447 -0.2269 1.7041 0.9900
1.11022302463e-16
MCF10A-GM_6
 Taxol 72 0.0035 -0.2324 0.7521 0.00448 -0.2160 1.4996 0.9915
1.11022302463e-16
MCF10A-GM_5
 Taxol 72 0.0035 -0.2405 0.7502 0.00450 -0.2273 1.5202 0.9935
1.11022302463e-16
MCF10A-GM_4
 Taxol 72 0.0036 -0.2361 0.7531 0.00459 -0.2325 1.5776 0.9936
1.11022302463e-16
MCF10A-GM_7
 Taxol 72 0.0037 -0.2470 0.7442 0.00467 -0.2327 1.6111 0.9916
1.11022302463e-16
MCF10A-GM_9
 Taxol 72 0.0037 -0.2442 0.7335 0.00470 -0.2263 1.6044 0.9924
1.11022302463e-16
MCF10A-GM_8
 Taxol 72 0.0041 -0.2560 0.7346 0.00512 -0.2260 1.6494 0.9902
1.11022302463e-16
MCF10A-GM_1
 Neratinib 72 0.1969 0.0642 0.3725 0.18049 0.0506 1.2255 0.8983
1.20580212482e-11
MCF10A-GM_2
 Neratinib 72 0.2054 0.0672 0.3563 0.18651 0.0602 1.3299 0.9097
3.26805249529e-12
MCF10A-GM_3
 Neratinib 72 0.2022 0.0710 0.3721 0.18743 0.0439 1.2090 0.8942
1.85039761291e-11
MCF10A-GM_1
 Etoposide 72 0.2323 0.0175 0.4818 0.23150 0.0024 1.4514 0.9879
1.11022302463e-16
MCF10A-GM_3
 Etoposide 72 0.2400 0.0138 0.4788 0.24005 -0.0002 1.2891 0.9909
1.11022302463e-16
MCF10A-GM_2
 Etoposide 72 0.2479 0.0064 0.4665 0.24608 0.0050 1.3936 0.9932
1.11022302463e-16
MCF10A-GM_4
 Neratinib 72 0.3333 0.1249 0.2789 0.25439 0.1756 1.6016 0.8850
4.64310812021e-11
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