LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist A in 2019 to assess reproducibility. Dataset 2 of 2: Calculated dose response metrics. - Dataset (ID:20361)

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Cell Small Molecule Timepoint GR50 GRmax GR_AOC GEC50 GRinf h_GR r2_GR pval_GR
MCF10A-GM_1
 Alpelisib 72 8.2016 0.4069 0.1540 65.49912 -1.0000 0.5288 0.9578
7.77156117238e-16
MCF10A-GM_1
 Dasatinib 72 0.2837 -0.1309 0.4667 0.43854 -0.2021 0.7795 0.9729
1.11022302463e-16
MCF10A-GM_1
 Etoposide 72 0.2323 0.0175 0.4818 0.23150 0.0024 1.4514 0.9879
1.11022302463e-16
MCF10A-GM_1
 Neratinib 72 0.1969 0.0642 0.3725 0.18049 0.0506 1.2255 0.8983
1.20580212482e-11
MCF10A-GM_1
 Taxol 72 0.0036 -0.2565 0.7506 0.00447 -0.2269 1.7041 0.9900
1.11022302463e-16
MCF10A-GM_1
 Palbociclib 72 0.3755 0.0386 0.3583 0.32427 0.0472 0.6762 0.9684
9.82769421398e-13
MCF10A-GM_1
 Trametinib 72 0.0037 0.0635 0.6324 0.00299 0.1133 1.2768 0.9809
1.11022302463e-16
MCF10A-GM_1
 Vorinostat 72 1.1221 0.0197 0.2903 1.23808 -0.0618 1.1857 0.9886
1.11022302463e-16
MCF10A-GM_2
 Alpelisib 72 7.3886 0.4254 0.1560 53.37110 -1.0000 0.5556 0.9629
2.22044604925e-16
MCF10A-GM_2
 Dasatinib 72 0.3007 -0.1486 0.4680 0.61942 -0.3062 0.6611 0.9635
1.11022302463e-16
MCF10A-GM_2
 Etoposide 72 0.2479 0.0064 0.4665 0.24608 0.0050 1.3936 0.9932
1.11022302463e-16
MCF10A-GM_2
 Neratinib 72 0.2054 0.0672 0.3563 0.18651 0.0602 1.3299 0.9097
3.26805249529e-12
MCF10A-GM_2
 Taxol 72 0.0034 -0.2221 0.7684 0.00420 -0.2170 1.6095 0.9928
1.11022302463e-16
MCF10A-GM_2
 Palbociclib 72 0.5075 0.1059 0.3396 0.44124 0.0438 0.6549 0.9544
1.88525861589e-11
MCF10A-GM_2
 Trametinib 72 0.0031 0.0932 0.6454 0.00247 0.1261 1.2703 0.9864
1.11022302463e-16
MCF10A-GM_2
 Vorinostat 72 1.1217 0.0167 0.2934 1.30060 -0.0891 1.1078 0.9862
1.11022302463e-16
MCF10A-GM_3
 Alpelisib 72 7.4487 0.4036 0.1516 49.04215 -1.0000 0.5829 0.9653
1.11022302463e-16
MCF10A-GM_3
 Dasatinib 72 0.3180 -0.1962 0.4706 0.67309 -0.3178 0.6561 0.9749
1.11022302463e-16
MCF10A-GM_3
 Etoposide 72 0.2400 0.0138 0.4788 0.24005 -0.0002 1.2891 0.9909
1.11022302463e-16
MCF10A-GM_3
 Neratinib 72 0.2022 0.0710 0.3721 0.18743 0.0439 1.2090 0.8942
1.85039761291e-11
MCF10A-GM_3
 Taxol 72 0.0032 -0.2644 0.7716 0.00409 -0.2204 1.5590 0.9925
1.11022302463e-16
MCF10A-GM_3
 Palbociclib 72 0.6883 0.0974 0.3032 0.58742 0.0550 0.7356 0.9773
6.93889390391e-14
MCF10A-GM_3
 Trametinib 72 0.0032 0.0891 0.6444 0.00254 0.1236 1.1674 0.9882
1.11022302463e-16
MCF10A-GM_3
 Vorinostat 72 1.1270 0.0140 0.2901 1.24865 -0.0667 1.2227 0.9848
1.11022302463e-16
MCF10A-GM_4
 Alpelisib 72 9.9368 0.4353 0.1434 78.91713 -1.0000 0.5302 0.9350
8.71525074331e-14
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