LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 45.25 | 13.3 | 1.4887 | 1.597 | -0.1303 | -0.1190 | 3.1231 | 0.2478 |
| MCF 10A-H2B-mCherry | Vorinostat | 63.02 | 13.3 | 2.2236 | 2.2495 | -0.0400 | -0.0312 | 5.0000 | 0.1616 |
| MCF 10A-H2B-mCherry | Vorinostat | 27.48 | 13.3 | 0.6823 | 0.8212 | -0.1496 | -0.1683 | 1.6127 | 0.3903 |
| MCF 10A-H2B-mCherry | Vorinostat | 43.03 | 13.3 | 1.3344 | 1.4263 | -0.1272 | -0.1046 | 3.1385 | 0.2693 |
| MCF 10A-H2B-mCherry | Vorinostat | 54.14 | 13.3 | 1.8708 | 1.9209 | -0.0884 | -0.0604 | 4.4214 | 0.1907 |
| MCF 10A-H2B-mCherry | Vorinostat | 60.80 | 13.3 | 2.2188 | 2.2676 | -0.0773 | -0.0554 | 4.8049 | 0.1568 |
| MCF 10A-H2B-mCherry | Vorinostat | 18.59 | 13.3 | 0.5664 | 1.0687 | -0.2412 | -0.4101 | 0.9460 | 0.4283 |
| MCF 10A-H2B-mCherry | Vorinostat | 25.25 | 13.3 | 0.5644 | 0.7187 | -0.1603 | -0.1877 | 1.3197 | 0.4052 |
| MCF 10A-H2B-mCherry | Vorinostat | 34.14 | 13.3 | 1.068 | 1.1653 | -0.1206 | -0.1119 | 3.4369 | 0.3330 |
| MCF 10A-H2B-mCherry | Vorinostat | 40.81 | 13.3 | 1.1984 | 1.2893 | -0.0960 | -0.1017 | 2.5017 | 0.3013 |
| MCF 10A-H2B-mCherry | Vorinostat | 49.69 | 13.3 | 1.7722 | 1.8866 | -0.1393 | -0.1148 | 3.5508 | 0.2155 |
| MCF 10A-H2B-mCherry | Vorinostat | 51.92 | 13.3 | 1.8216 | 1.8954 | -0.1164 | -0.0792 | 4.1224 | 0.2010 |
| MCF 10A-H2B-mCherry | Vorinostat | 56.36 | 13.3 | 1.8971 | 1.9476 | -0.1068 | -0.0598 | 4.3974 | 0.1866 |
| MCF 10A-H2B-mCherry | Vorinostat | 58.58 | 13.3 | 2.0321 | 2.0717 | -0.0920 | -0.0454 | 4.6303 | 0.1798 |
| MCF 10A-H2B-mCherry | Vorinostat | 15.91 | 13.5 | 0.673 | 1.0022 | -0.2338 | -0.3147 | 1.2258 | 0.4090 |
| MCF 10A-H2B-mCherry | Vorinostat | 16.73 | 13.3 | 0.6881 | 1.3581 | -0.2534 | -0.4659 | 0.9685 | 0.4010 |
| MCF 10A-H2B-mCherry | Vorinostat | 20.81 | 13.3 | 0.502 | 0.8536 | -0.2101 | -0.3304 | 0.9626 | 0.4380 |
| MCF 10A-H2B-mCherry | Vorinostat | 23.04 | 13.3 | 0.5079 | 0.7078 | -0.1692 | -0.2294 | 1.1387 | 0.4288 |
| MCF 10A-H2B-mCherry | Vorinostat | 29.70 | 13.3 | 0.765 | 0.8757 | -0.1253 | -0.1391 | 1.8944 | 0.3675 |
| MCF 10A-H2B-mCherry | Vorinostat | 31.92 | 13.3 | 0.9055 | 1.0076 | -0.1133 | -0.1220 | 2.1792 | 0.3507 |
| MCF 10A-H2B-mCherry | Vorinostat | 36.36 | 13.3 | 1.0762 | 1.2153 | -0.1104 | -0.1406 | 2.2647 | 0.3356 |
| MCF 10A-H2B-mCherry | Vorinostat | 38.59 | 13.3 | 1.1098 | 1.2326 | -0.1011 | -0.1245 | 2.1821 | 0.3320 |
| MCF 10A-H2B-mCherry | Vorinostat | 47.47 | 13.3 | 1.6384 | 1.7629 | -0.1376 | -0.1259 | 3.2107 | 0.2336 |
| MCF 10A-H2B-mCherry | Vorinostat | 67.47 | 13.3 | 2.8259 | 2.865 | -0.0319 | -0.0356 | 5.0000 | 0.1279 |
| MCF 10A-H2B-mCherry | Vorinostat | 65.24 | 13.3 | 2.4454 | 2.4775 | -0.0465 | -0.0353 | 5.0000 | 0.1445 |