LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 25.25 | 13.3 | 0.0019 | 0.0035 | -0.7891 | -0.6591 | 1.4064 | 0.8233 |
| MCF 10A-H2B-mCherry | Taxol | 23.04 | 13.3 | 0.002 | 0.0039 | -0.7844 | -0.6681 | 1.2967 | 0.8096 |
| MCF 10A-H2B-mCherry | Taxol | 20.81 | 13.3 | 0.0024 | 0.0055 | -0.7843 | -0.7290 | 1.0789 | 0.7803 |
| MCF 10A-H2B-mCherry | Taxol | 27.48 | 13.3 | 0.0019 | 0.0032 | -0.7766 | -0.6351 | 1.5305 | 0.8280 |
| MCF 10A-H2B-mCherry | Taxol | 29.70 | 13.3 | 0.0018 | 0.0028 | -0.7417 | -0.6033 | 1.6514 | 0.8307 |
| MCF 10A-H2B-mCherry | Taxol | 18.59 | 13.3 | 0.0034 | 0.0077 | -0.7352 | -0.7179 | 1.1107 | 0.7117 |
| MCF 10A-H2B-mCherry | Taxol | 15.91 | 13.5 | 0.0055 | 0.0121 | -0.6952 | -0.7201 | 1.1326 | 0.6312 |
| MCF 10A-H2B-mCherry | Taxol | 16.73 | 13.3 | 0.0047 | 0.0097 | -0.6834 | -0.7046 | 1.2187 | 0.6742 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.82 | 13.4 | 2.6268 | 3.1186 | -0.6670 | -0.6812 | 5.0000 | 0.2539 |
| MCF 10A-H2B-mCherry | Taxol | 31.92 | 13.3 | 0.0016 | 0.0025 | -0.6609 | -0.5655 | 1.5990 | 0.8378 |
| MCF 10A-H2B-mCherry | Taxol | 34.14 | 13.3 | 0.0015 | 0.0022 | -0.6309 | -0.4906 | 1.7169 | 0.8190 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.38 | 13.4 | 2.6411 | 3.1142 | -0.6260 | -0.6410 | 5.0000 | 0.2153 |
| MCF 10A-H2B-mCherry | Dasatinib | 78.60 | 13.4 | 2.6077 | 3.0672 | -0.6115 | -0.6256 | 5.0000 | 0.2331 |
| MCF 10A-H2B-mCherry | Dasatinib | 74.16 | 13.4 | 2.6047 | 3.0088 | -0.5134 | -0.5296 | 5.0000 | 0.2140 |
| MCF 10A-H2B-mCherry | Taxol | 36.36 | 13.3 | 0.0014 | 0.002 | -0.5106 | -0.4415 | 1.8237 | 0.8179 |
| MCF 10A-H2B-mCherry | Taxol | 38.59 | 13.3 | 0.0013 | 0.0018 | -0.5016 | -0.3717 | 2.0884 | 0.8013 |
| MCF 10A-H2B-mCherry | Dasatinib | 71.94 | 13.4 | 2.6626 | 3.0476 | -0.4700 | -0.4838 | 5.0000 | 0.1943 |
| MCF 10A-H2B-mCherry | Taxol | 78.60 | 13.4 | 0.0027 | 0.003 | -0.4567 | -0.3897 | 5.0000 | 0.7535 |
| MCF 10A-H2B-mCherry | Neratinib | 74.16 | 13.4 | 1.0683 | 1.3539 | -0.4211 | -0.7255 | 3.7652 | 0.1930 |
| MCF 10A-H2B-mCherry | Taxol | 80.82 | 13.4 | 0.0029 | 0.0033 | -0.4208 | -0.4210 | 5.0000 | 0.7492 |
| MCF 10A-H2B-mCherry | Taxol | 71.94 | 13.4 | 0.0024 | 0.0025 | -0.4059 | -0.1917 | 5.0000 | 0.6660 |
| MCF 10A-H2B-mCherry | Taxol | 43.03 | 13.3 | 0.0014 | 0.0016 | -0.3983 | -0.2791 | 2.7072 | 0.7654 |
| MCF 10A-H2B-mCherry | Taxol | 40.81 | 13.3 | 0.0013 | 0.0017 | -0.3971 | -0.3361 | 2.3974 | 0.7895 |
| MCF 10A-H2B-mCherry | Taxol | 76.38 | 13.4 | 0.0027 | 0.003 | -0.3872 | -0.2827 | 5.0000 | 0.7081 |
| MCF 10A-H2B-mCherry | Neratinib | 76.38 | 13.4 | 1.1623 | 1.4074 | -0.3862 | -0.4851 | 3.9610 | 0.2050 |