LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)

Data Columns

  • 10 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
cell
Cell reagent
Cell cell
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
timePointHr
End time point of rolling window (in hr; averaged across technical replicates)
Time Point (hr) Numeric hr 2
timeIntervalHr
Total time from start to end of rolling window (in hr; averaged across technical replicates)
Time Interval (hr) Numeric hr 1
gR50
Small molecule concentration in uM at which GR(c)=0.5
GR50 Text
gEC50
Small molecule concentration in uM that results in 50% efficacy
GEC50 Text
gRmax
Normalized growth inhibition rate at the highest tested concentration
GRmax Numeric 4
gRinf
Asymptotic value (concentration = infinity) for the sigmoidal curve fit to the dose-response data
GRinf Numeric 4
gRHillCoefficient
Maximal slope of the dose-response curve
GR Hill Coefficient Numeric 4
gRAOC
Integral of GR(c) over the range of concentrations tested
GR_AOC Numeric 4
  • 10 Data Columns