LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Alpelisib 15.91 13.5
18.5716
168.3795
0.5685 -1.0000 0.4983 0.1166
MCF 10A-H2B-mCherry Alpelisib 16.73 13.3
19.6489
124.3425
0.6341 -0.9991 0.5951 0.0849
MCF 10A-H2B-mCherry Alpelisib 18.59 13.3
16.2872
30.1363
0.5697 -0.4075 0.6604 0.1016
MCF 10A-H2B-mCherry Alpelisib 20.81 13.3
15.1045
119.1663
0.5557 -1.0000 0.5491 0.1104
MCF 10A-H2B-mCherry Alpelisib 23.04 13.3
13.0191
67.1327
0.5327 -1.0000 0.6881 0.0949
MCF 10A-H2B-mCherry Alpelisib 25.25 13.3
13.7447
50.8693
0.5662 -0.9329 0.8377 0.0699
MCF 10A-H2B-mCherry Alpelisib 27.48 13.3
20.0615
109.7735
0.5940 -1.0000 0.7179 0.0765
MCF 10A-H2B-mCherry Alpelisib 29.70 13.3
27.7483
154.7888
0.6373 -0.8744 0.6097 0.0762
MCF 10A-H2B-mCherry Alpelisib 31.92 13.3
Inf
48.0469
0.6505 -0.3257 0.5441 0.0840
MCF 10A-H2B-mCherry Alpelisib 34.14 13.3
33.6323
138.7884
0.6705 -0.6260 0.5249 0.0816
MCF 10A-H2B-mCherry Alpelisib 36.36 13.3
42.9745
417.2033
0.6921 -0.9983 0.4876 0.0807
MCF 10A-H2B-mCherry Alpelisib 38.59 13.3
Inf
659.7431
0.7083 -0.8898 0.4399 0.0784
MCF 10A-H2B-mCherry Alpelisib 40.81 13.3
42.2866
311.4568
0.7077 -1.0000 0.5651 0.0697
MCF 10A-H2B-mCherry Alpelisib 43.03 13.3
23.3924
88.1783
0.7153 -0.9969 0.8352 0.0518
MCF 10A-H2B-mCherry Alpelisib 45.25 13.3
Inf
19.4732
0.7923 -0.0908 3.0690 0.0228
MCF 10A-H2B-mCherry Alpelisib 47.47 13.3
Inf
17.0493
0.7926 -0.0881 3.2633 0.0135
MCF 10A-H2B-mCherry Alpelisib 49.69 13.3
Inf
15.168
0.7888 -0.0845 3.1051 0.0197
MCF 10A-H2B-mCherry Alpelisib 51.92 13.3
Inf
21.8307
0.7677 -0.1382 1.2490 0.0308
MCF 10A-H2B-mCherry Alpelisib 54.14 13.3
Inf
12.3614
0.7650 -0.1089 1.4676 0.0227
MCF 10A-H2B-mCherry Alpelisib 56.36 13.3
Inf
12.6838
0.7979 -0.0976 1.4912 0.0136
MCF 10A-H2B-mCherry Alpelisib 58.58 13.3
Inf
14.2616
0.7902 -0.1257 1.4055 0.0230
MCF 10A-H2B-mCherry Alpelisib 60.80 13.3
Inf
Inf
0.7722 0.8272 1.1247 0.0073
MCF 10A-H2B-mCherry Alpelisib 63.02 13.3
Inf
Inf
0.8310 0.8049 0.7013 0.0213
MCF 10A-H2B-mCherry Alpelisib 65.24 13.3
Inf
Inf
0.7691 0.8264 2.5000 0.0249
MCF 10A-H2B-mCherry Alpelisib 67.47 13.3
Inf
Inf
0.8446 0.8821 2.5000 0.0200
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