Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 500.0 | ng/ml | 2 | -4.31 | 71.7160 | 0.000 | 0.97284 | 0.94815 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 1 | -4.31 | 66.9521 | 0.000 | 0.96986 | 0.90411 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 50.0 | ng/ml | 2 | -4.76 | 163.3246 | 0.000 | 0.99474 | 0.97544 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 50.0 | ng/ml | 1 | -4.84 | 188.4868 | 0.000 | 1.00000 | 0.89474 | ||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 500.0 | ng/ml | 3 | -4.16 | 43.5669 | 0.000 | 0.94268 | 0.83439 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 2 | -4.37 | 81.7724 | 0.002 | 0.99067 | 0.94403 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 500.0 | ng/ml | 1 | -4.25 | 57.6070 | 0.002 | 0.97623 | 0.83360 | ||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 500.0 | ng/ml | 3 | -4.18 | 46.9408 | 0.007 | 0.93421 | 0.83553 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | anti-Fc | 10.0 | nM | 2 | -4.93 | 186.2624 | 0.010 | 0.90759 | 0.68812 | |||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | anti-Fc | 10.0 | nM | 1 | -4.70 | 139.7368 | 0.011 | 0.92026 | 0.78469 | |||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 7.5 | ng/ml | 1 | -5.38 | 333.0821 | 0.012 | 0.94807 | 0.44891 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 500.0 | ng/ml | 1 | -4.30 | 54.0650 | 0.013 | 0.98211 | 0.80813 | ||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 3 | -4.18 | 49.8951 | 0.014 | 0.90909 | 0.88112 | |||||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 1 | -4.39 | 70.4229 | 0.016 | 0.98363 | 0.90177 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 500.0 | ng/ml | 2 | -4.23 | 47.4504 | 0.018 | 0.94643 | 0.78770 | ||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 3 | -4.26 | 52.9167 | 0.025 | 0.87255 | 0.84314 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | 1 | -5.47 | 338.7050 | 0.034 | 0.89448 | 0.31894 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 3 | -4.17 | 41.8056 | 0.039 | 0.93333 | 0.74722 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 2 | -4.29 | 57.5746 | 0.045 | 0.94030 | 0.85634 | ||||||
| HeLa ICRP | TNF10 | 500.0 | ng/ml | 1 | -4.34 | 67.5100 | 0.045 | 0.89348 | 0.86285 | |||||||||
| HeLa ICRP | TNF10 | 500.0 | ng/ml | 3 | -4.26 | 58.7068 | 0.046 | 0.90595 | 0.86030 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 3 | -4.34 | 68.5914 | 0.058 | 0.88387 | 0.88172 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 4 | -4.34 | 69.2257 | 0.059 | 0.89621 | 0.88138 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 1 | -4.43 | 88.9362 | 0.060 | 0.90780 | 0.91064 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 6 | -4.22 | 51.3152 | 0.063 | 0.88662 | 0.85034 |