Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Protein Concentration Protein Conc Unit Antibody Name Antibody Concentration Antibody Conc Unit 2nd Antibody Name 2nd Antibody Concentration 2nd Antibody Conc Unit Replicate Mean log10(k) (a.u.) Mean tau (min) Surviving Fraction Classification Accuracy (theta_T) Classification Accuracy (fate boundary)
HeLa ICRP Bortezomib 100
nM
Mapatumumab
 10.0
nM
 2 -5.47 319.6967 0.075 0.86936 0.30949
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
ng/ml
anti-Fc
 25.0
ng/ml
 1 -5.30 298.2392 0.073 0.94086 0.48387
HeLa ICRP Bortezomib 100
nM
 TNF10 7.5
ng/ml
 2 -5.69 426.8136 0.208 0.91182 0.36673
HeLa ICRP Bortezomib 100
nM
Mapatumumab
 10.0
nM
 1 -5.47 338.7050 0.034 0.89448 0.31894
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
nM
 2 -5.39 331.3306 0.083 0.86694 0.49064
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
nM
 5 -6.05 472.6445 0.683 0.94218 0.72805
HeLa ICRP Bortezomib 100
nM
 TNF10 5.0
ng/ml
 1 -5.56 416.4737 0.358 0.94737 0.58947
HeLa ICRP Bortezomib 100
nM
 TNF10 7.5
ng/ml
 1 -5.38 333.0821 0.012 0.94807 0.44891
HeLa ICRP Bortezomib 100
nM
 TNF10 250.0
ng/ml
 1 -4.31 66.9521 0.000 0.96986 0.90411
HeLa ICRP Bortezomib 100
nM
 TNF10 500.0
ng/ml
 2 -4.31 71.7160 0.000 0.97284 0.94815
HeLa ICRP Bortezomib 100
nM
Mapatumumab
 10.0
nM
anti-Fc
 10.0
nM
 2 -4.93 186.2624 0.010 0.90759 0.68812
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
nM
 1 -6.20 481.7639 0.801 0.96817 0.78780
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
nM
 3 -6.35 445.1084 0.889 0.98103 0.88889
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
nM
 4 -6.21 485.6552 0.814 0.97069 0.80517
HeLa ICRP Bortezomib 100
nM
 TNF10 1.0
ng/ml
 1 -6.43 491.0887 1.000 0.99194 0.96774
HeLa ICRP Bortezomib 100
nM
 TNF10 1.0
ng/ml
 2 -6.32 468.5230 0.965 0.99344 0.91028
HeLa ICRP Bortezomib 100
nM
 TNF10 5.0
ng/ml
 2 -5.53 404.8037 0.065 0.83770 0.38743
HeLa ICRP Bortezomib 100
nM
 TNF10 5.0
ng/ml
 3 -5.79 469.2892 0.407 0.88235 0.52941
HeLa ICRP Bortezomib 100
nM
 TNF10 50.0
ng/ml
 1 -4.84 188.4868 0.000 1.00000 0.89474
HeLa ICRP Bortezomib 100
nM
 TNF10 50.0
ng/ml
 2 -4.76 163.3246 0.000 0.99474 0.97544
HeLa ICRP Bortezomib 100
nM
 TNF10 250.0
ng/ml
 2 -4.37 81.7724 0.002 0.99067 0.94403
HeLa ICRP Bortezomib 100
nM
 TNF10 500.0
ng/ml
 1 -4.25 57.6070 0.002 0.97623 0.83360
HeLa ICRP Bortezomib 100
nM
Mapatumumab
 10.0
nM
anti-Fc
 10.0
nM
 1 -4.70 139.7368 0.011 0.92026 0.78469
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
ng/ml
anti-Fc
 25.0
ng/ml
 3 -5.87 409.3750 0.568 0.88750 0.68250
HeLa ICRP Bortezomib 100
nM
Apomab
 25.0
ng/ml
anti-Fc
 25.0
ng/ml
 2 -5.36 315.9300 0.077 0.87923 0.49275
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