Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.19 | 81.1458 | 0.917 | 0.25000 | 0.08333 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 500.0 | ng/ml | 2 | -4.02 | 73.1522 | 0.880 | 0.19565 | 0.08696 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.04 | 75.6780 | 0.898 | 0.18644 | 0.10169 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.05 | 77.8723 | 0.936 | 0.12766 | 0.10638 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 5 | -4.01 | 69.8361 | 0.836 | 0.18033 | 0.13115 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 500.0 | ng/ml | 1 | -4.04 | 70.9259 | 0.864 | 0.20988 | 0.13580 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 1 | -4.03 | 68.4836 | 0.803 | 0.26230 | 0.17213 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 500.0 | ng/ml | 1 | -3.94 | 63.4836 | 0.746 | 0.27049 | 0.20492 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 5 | -4.03 | 76.7361 | 0.792 | 0.22222 | 0.20833 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.15 | 84.0957 | 0.777 | 0.25532 | 0.22340 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 1 | -4.02 | 64.6000 | 0.740 | 0.34000 | 0.24000 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 500.0 | ng/ml | 2 | -4.09 | 66.3725 | 0.706 | 0.37255 | 0.25490 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | 2 | -5.47 | 319.6967 | 0.075 | 0.86936 | 0.30949 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | 1 | -5.47 | 338.7050 | 0.034 | 0.89448 | 0.31894 | ||||||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 3 | -5.43 | 292.5407 | 0.270 | 0.61564 | 0.35505 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 7.5 | ng/ml | 2 | -5.69 | 426.8136 | 0.208 | 0.91182 | 0.36673 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 5.0 | ng/ml | 2 | -5.53 | 404.8037 | 0.065 | 0.83770 | 0.38743 | ||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 25.0 | ng/ml | 1 | -5.09 | 259.4385 | 0.914 | 0.41711 | 0.39572 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | ng/ml | anti-Fc | 25.0 | ng/ml | 5 | -5.44 | 331.4063 | 0.076 | 0.91071 | 0.41295 | |||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 7.5 | ng/ml | 1 | -5.38 | 333.0821 | 0.012 | 0.94807 | 0.44891 | ||||||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 1 | -5.13 | 210.4954 | 0.132 | 0.56697 | 0.47890 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | ng/ml | anti-Fc | 25.0 | ng/ml | 1 | -5.30 | 298.2392 | 0.073 | 0.94086 | 0.48387 | |||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | nM | 2 | -5.39 | 331.3306 | 0.083 | 0.86694 | 0.49064 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | ng/ml | anti-Fc | 25.0 | ng/ml | 2 | -5.36 | 315.9300 | 0.077 | 0.87923 | 0.49275 | |||
| HeLa ICRP Bcl-XL-mCherry | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 2 | -4.03 | 54.5000 | 0.400 | 0.60000 | 0.50000 |