Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 1 | -6.60 | 379.1667 | 0.958 | 0.95833 | 1.00000 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 50.0 | ng/ml | 2 | -4.76 | 163.3246 | 0.000 | 0.99474 | 0.97544 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 1.0 | ng/ml | 1 | -6.43 | 491.0887 | 1.000 | 0.99194 | 0.96774 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 500.0 | ng/ml | 2 | -4.31 | 71.7160 | 0.000 | 0.97284 | 0.94815 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 2 | -4.37 | 81.7724 | 0.002 | 0.99067 | 0.94403 | ||||||
| HeLa ICRP FLIP-S-mCherry | TNF10 | 250.0 | ng/ml | 3 | -5.44 | 149.9528 | 0.651 | 0.96226 | 0.91509 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 1 | -4.43 | 88.9362 | 0.060 | 0.90780 | 0.91064 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 1.0 | ng/ml | 2 | -6.32 | 468.5230 | 0.965 | 0.99344 | 0.91028 | ||||||
| HeLa ICRP | TNF10 | 5.0 | ng/ml | 2 | -5.94 | 296.5797 | 0.901 | 0.93913 | 0.91014 | |||||||||
| HeLa ICRP | TNF10 | 5.0 | ng/ml | 3 | -6.20 | 283.4633 | 0.895 | 0.92202 | 0.90826 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 1 | -4.31 | 66.9521 | 0.000 | 0.96986 | 0.90411 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 1 | -4.39 | 70.4229 | 0.016 | 0.98363 | 0.90177 | ||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 3 | -6.59 | 286.3068 | 0.949 | 0.96591 | 0.89773 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 50.0 | ng/ml | 1 | -4.84 | 188.4868 | 0.000 | 1.00000 | 0.89474 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | nM | 3 | -6.35 | 445.1084 | 0.889 | 0.98103 | 0.88889 | ||||||
| HeLa ICRP | Apomab | 25.0 | nM | anti-Fc | 25.0 | nM | 4 | -6.12 | 272.4815 | 0.907 | 0.92963 | 0.88889 | ||||||
| HeLa ICRP | Apomab | 25.0 | nM | 5 | -6.58 | 309.2188 | 0.901 | 0.90865 | 0.88462 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 3 | -6.37 | 263.5100 | 0.877 | 0.87966 | 0.88252 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 3 | -4.34 | 68.5914 | 0.058 | 0.88387 | 0.88172 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 2 | -6.45 | 249.8519 | 0.956 | 0.97037 | 0.88148 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 4 | -4.34 | 69.2257 | 0.059 | 0.89621 | 0.88138 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 3 | -4.18 | 49.8951 | 0.014 | 0.90909 | 0.88112 | |||||||||
| HeLa ICRP | Apomab | 200.0 | nM | anti-Fc | 200.0 | nM | 2 | -5.80 | 251.2577 | 0.896 | 0.95706 | 0.87730 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 1.0 | ng/ml | 2 | -6.56 | 276.5333 | 0.964 | 0.98667 | 0.87556 | ||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 2 | -4.42 | 90.1432 | 0.101 | 0.89648 | 0.87225 |