Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 500.0 | ng/ml | 1 | -4.30 | 54.0650 | 0.013 | 0.98211 | 0.80813 | ||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | 1 | -5.21 | 212.5904 | 0.659 | 0.86345 | 0.76707 | |||||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 1.0 | ng/ml | 1 | -6.45 | 316.4894 | 0.957 | 0.97872 | 0.82979 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 1 | -4.39 | 70.4229 | 0.016 | 0.98363 | 0.90177 | ||||||
| HeLa ICRP | Mapatumumab | 5.0 | nM | 1 | -5.33 | 226.3964 | 0.694 | 0.89790 | 0.77778 | |||||||||
| HeLa ICRP | Mapatumumab | 10.0 | nM | 1 | -5.46 | 256.4570 | 0.735 | 0.86093 | 0.77815 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 7.5 | ng/ml | 1 | -5.38 | 333.0821 | 0.012 | 0.94807 | 0.44891 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 500.0 | ng/ml | 1 | -4.25 | 57.6070 | 0.002 | 0.97623 | 0.83360 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 25.0 | ng/ml | 1 | -5.21 | 240.5391 | 0.249 | 0.91826 | 0.63304 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 50.0 | ng/ml | 1 | -4.78 | 147.7273 | 0.121 | 0.93939 | 0.78788 | ||||||
| HeLa ICRP | Mapatumumab | 2.5 | nM | 1 | -5.58 | 245.7329 | 0.779 | 0.89251 | 0.83713 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 5.0 | ng/ml | 1 | -5.56 | 416.4737 | 0.358 | 0.94737 | 0.58947 | ||||||
| HeLa ICRP | TNF10 | 50.0 | ng/ml | 1 | -4.71 | 138.0000 | 0.400 | 0.68889 | 0.60000 | |||||||||
| HeLa ICRP | TNF10 | 7.5 | ng/ml | 1 | -5.81 | 277.9023 | 0.825 | 0.92241 | 0.85057 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 1 | -4.43 | 88.9362 | 0.060 | 0.90780 | 0.91064 | |||||||||
| HeLa ICRP | TNF10 | 5.0 | ng/ml | 1 | -5.80 | 282.0968 | 0.839 | 0.93548 | 0.80645 | |||||||||
| HeLa ICRP | TNF10 | 10.0 | ng/ml | 1 | -5.50 | 258.7097 | 0.742 | 0.90323 | 0.83871 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 1 | -4.31 | 66.9521 | 0.000 | 0.96986 | 0.90411 | ||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 1 | -6.60 | 379.1667 | 0.958 | 0.95833 | 1.00000 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 1.0 | ng/ml | 1 | -6.43 | 491.0887 | 1.000 | 0.99194 | 0.96774 | ||||||
| HeLa ICRP | TNF10 | 500.0 | ng/ml | 1 | -4.34 | 67.5100 | 0.045 | 0.89348 | 0.86285 | |||||||||
| HeLa ICRP | TNF10 | 25.0 | ng/ml | 1 | -5.14 | 214.7516 | 0.457 | 0.83540 | 0.65528 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 50.0 | ng/ml | 1 | -4.84 | 188.4868 | 0.000 | 1.00000 | 0.89474 | ||||||
| HeLa ICRP | Mapatumumab | 200.0 | nM | 1 | -4.94 | 155.5995 | 0.386 | 0.81055 | 0.74820 | |||||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | 1 | -5.11 | 190.0427 | 0.604 | 0.84046 | 0.71225 |