Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.05 | 77.8723 | 0.936 | 0.12766 | 0.10638 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 5 | -4.01 | 69.8361 | 0.836 | 0.18033 | 0.13115 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.04 | 75.6780 | 0.898 | 0.18644 | 0.10169 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 500.0 | ng/ml | 2 | -4.02 | 73.1522 | 0.880 | 0.19565 | 0.08696 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 500.0 | ng/ml | 1 | -4.04 | 70.9259 | 0.864 | 0.20988 | 0.13580 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 5 | -4.03 | 76.7361 | 0.792 | 0.22222 | 0.20833 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.19 | 81.1458 | 0.917 | 0.25000 | 0.08333 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.15 | 84.0957 | 0.777 | 0.25532 | 0.22340 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 1 | -4.03 | 68.4836 | 0.803 | 0.26230 | 0.17213 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 500.0 | ng/ml | 1 | -3.94 | 63.4836 | 0.746 | 0.27049 | 0.20492 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 1 | -4.02 | 64.6000 | 0.740 | 0.34000 | 0.24000 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 500.0 | ng/ml | 2 | -4.09 | 66.3725 | 0.706 | 0.37255 | 0.25490 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 25.0 | ng/ml | 1 | -5.09 | 259.4385 | 0.914 | 0.41711 | 0.39572 | |||||||||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 1 | -5.13 | 210.4954 | 0.132 | 0.56697 | 0.47890 | ||||||
| HeLa ICRP Bcl-XL-mCherry | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 2 | -4.03 | 54.5000 | 0.400 | 0.60000 | 0.50000 | ||||||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 3 | -5.43 | 292.5407 | 0.270 | 0.61564 | 0.35505 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 2 | -4.57 | 88.4746 | 0.369 | 0.65085 | 0.66780 | ||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 25.0 | ng/ml | 2 | -5.41 | 255.1832 | 0.916 | 0.65445 | 0.56021 | |||||||||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 2 | -5.11 | 216.4074 | 0.167 | 0.65556 | 0.58889 | ||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 2 | -4.55 | 92.1239 | 0.381 | 0.66372 | 0.64307 | ||||||
| HeLa ICRP | Mapatumumab | 10.0 | nM | anti-Fc | 10.0 | nM | 1 | -4.49 | 83.0851 | 0.309 | 0.68617 | 0.65691 | ||||||
| HeLa ICRP | TNF10 | 50.0 | ng/ml | 1 | -4.71 | 138.0000 | 0.400 | 0.68889 | 0.60000 | |||||||||
| HeLa ICRP | Mapatumumab | 5.0 | nM | anti-Fc | 5.0 | nM | 1 | -4.80 | 134.6580 | 0.476 | 0.71010 | 0.61238 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | 2 | -4.60 | 107.2881 | 0.373 | 0.72155 | 0.70460 | |||||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 1 | -4.50 | 85.1585 | 0.268 | 0.73592 | 0.70775 |