Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 50.0 | ng/ml | 1 | -4.84 | 188.4868 | 0.000 | 1.00000 | 0.89474 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 50.0 | ng/ml | 2 | -4.76 | 163.3246 | 0.000 | 0.99474 | 0.97544 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 1.0 | ng/ml | 2 | -6.32 | 468.5230 | 0.965 | 0.99344 | 0.91028 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 1.0 | ng/ml | 1 | -6.43 | 491.0887 | 1.000 | 0.99194 | 0.96774 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 2 | -4.37 | 81.7724 | 0.002 | 0.99067 | 0.94403 | ||||||
| HeLa ICRP | Apomab | 50.0 | nM | 2 | -6.48 | 250.9659 | 0.972 | 0.98864 | 0.80682 | |||||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 1.0 | ng/ml | 2 | -6.56 | 276.5333 | 0.964 | 0.98667 | 0.87556 | ||||||
| HeLa ICRP | Apomab | 100.0 | nM | 2 | -6.31 | 231.7647 | 0.971 | 0.98529 | 0.85294 | |||||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 1 | -4.39 | 70.4229 | 0.016 | 0.98363 | 0.90177 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 500.0 | ng/ml | 1 | -4.30 | 54.0650 | 0.013 | 0.98211 | 0.80813 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | nM | 3 | -6.35 | 445.1084 | 0.889 | 0.98103 | 0.88889 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 1.0 | ng/ml | 1 | -6.45 | 316.4894 | 0.957 | 0.97872 | 0.82979 | ||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 2 | -6.34 | 245.6857 | 0.977 | 0.97714 | 0.86286 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 500.0 | ng/ml | 1 | -4.25 | 57.6070 | 0.002 | 0.97623 | 0.83360 | ||||||
| HeLa ICRP | Apomab | 25.0 | nM | 1 | -6.44 | 211.4919 | 0.968 | 0.97581 | 0.75806 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 500.0 | ng/ml | 2 | -4.31 | 71.7160 | 0.000 | 0.97284 | 0.94815 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | nM | 4 | -6.21 | 485.6552 | 0.814 | 0.97069 | 0.80517 | ||||||
| HeLa ICRP | Apomab | 25.0 | nM | 2 | -6.45 | 249.8519 | 0.956 | 0.97037 | 0.88148 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 1 | -4.31 | 66.9521 | 0.000 | 0.96986 | 0.90411 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | nM | 1 | -6.20 | 481.7639 | 0.801 | 0.96817 | 0.78780 | ||||||
| HeLa ICRP | Apomab | 200.0 | nM | 1 | -6.25 | 250.2333 | 0.940 | 0.96667 | 0.85333 | |||||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 3 | -6.59 | 286.3068 | 0.949 | 0.96591 | 0.89773 | |||||||||
| HeLa ICRP | Apomab | 50.0 | nM | anti-Fc | 50.0 | nM | 2 | -5.58 | 216.2613 | 0.820 | 0.96396 | 0.81532 | ||||||
| HeLa ICRP FLIP-S-mCherry | TNF10 | 250.0 | ng/ml | 3 | -5.44 | 149.9528 | 0.651 | 0.96226 | 0.91509 | |||||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 1 | -6.60 | 379.1667 | 0.958 | 0.95833 | 1.00000 |