Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 1.0 | ng/ml | 1 | -6.43 | 491.0887 | 1.000 | 0.99194 | 0.96774 | ||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 2 | -6.34 | 245.6857 | 0.977 | 0.97714 | 0.86286 | |||||||||
| HeLa ICRP | Apomab | 50.0 | nM | 2 | -6.48 | 250.9659 | 0.972 | 0.98864 | 0.80682 | |||||||||
| HeLa ICRP | Apomab | 100.0 | nM | 2 | -6.31 | 231.7647 | 0.971 | 0.98529 | 0.85294 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 1 | -6.44 | 211.4919 | 0.968 | 0.97581 | 0.75806 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 1.0 | ng/ml | 2 | -6.32 | 468.5230 | 0.965 | 0.99344 | 0.91028 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 1.0 | ng/ml | 2 | -6.56 | 276.5333 | 0.964 | 0.98667 | 0.87556 | ||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 1 | -6.60 | 379.1667 | 0.958 | 0.95833 | 1.00000 | |||||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 1.0 | ng/ml | 1 | -6.45 | 316.4894 | 0.957 | 0.97872 | 0.82979 | ||||||
| HeLa ICRP | Apomab | 25.0 | nM | 2 | -6.45 | 249.8519 | 0.956 | 0.97037 | 0.88148 | |||||||||
| HeLa ICRP | Apomab | 50.0 | nM | 1 | -6.39 | 285.0388 | 0.953 | 0.95349 | 0.85271 | |||||||||
| HeLa ICRP | TNF10 | 1.0 | ng/ml | 3 | -6.59 | 286.3068 | 0.949 | 0.96591 | 0.89773 | |||||||||
| HeLa ICRP | Apomab | 200.0 | nM | 1 | -6.25 | 250.2333 | 0.940 | 0.96667 | 0.85333 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.05 | 77.8723 | 0.936 | 0.12766 | 0.10638 | |||||||||
| HeLa ICRP | Apomab | 100.0 | nM | 1 | -6.13 | 217.8947 | 0.934 | 0.92763 | 0.77632 | |||||||||
| HeLa ICRP | Apomab | 200.0 | nM | 2 | -6.34 | 213.4375 | 0.929 | 0.94643 | 0.78571 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.19 | 81.1458 | 0.917 | 0.25000 | 0.08333 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 25.0 | ng/ml | 2 | -5.41 | 255.1832 | 0.916 | 0.65445 | 0.56021 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 25.0 | ng/ml | 1 | -5.09 | 259.4385 | 0.914 | 0.41711 | 0.39572 | |||||||||
| HeLa ICRP | Apomab | 100.0 | nM | 3 | -6.54 | 273.3562 | 0.911 | 0.95205 | 0.84932 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | anti-Fc | 25.0 | nM | 4 | -6.12 | 272.4815 | 0.907 | 0.92963 | 0.88889 | ||||||
| HeLa ICRP | TNF10 | 5.0 | ng/ml | 2 | -5.94 | 296.5797 | 0.901 | 0.93913 | 0.91014 | |||||||||
| HeLa ICRP | Apomab | 25.0 | nM | 5 | -6.58 | 309.2188 | 0.901 | 0.90865 | 0.88462 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.04 | 75.6780 | 0.898 | 0.18644 | 0.10169 | |||||||||
| HeLa ICRP | Apomab | 200.0 | nM | anti-Fc | 200.0 | nM | 2 | -5.80 | 251.2577 | 0.896 | 0.95706 | 0.87730 |