Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Vemurafenib C32 3.1600
uM
 72
hr
 995 960 0.0153 0.0274 0.9648 0.9276 2
AZ-628 C32 3.1600
uM
 72
hr
 1046 997 0.0214 0.0269 0.9532 0.9414 1
Vemurafenib C32 3.1600
uM
 72
hr
 798 746 0.0227 0.0274 0.9348 0.9276 4
AZ-628 C32 3.1600
uM
 72
hr
 992 934 0.0253 0.0269 0.9415 0.9414 2
AZ-628 C32 3.1600
uM
 72
hr
 1133 1071 0.0271 0.0269 0.9453 0.9414 4
Vemurafenib C32 3.1600
uM
 72
hr
 998 921 0.0336 0.0274 0.9229 0.9276 1
AZ-628 C32 3.1600
uM
 72
hr
 1035 958 0.0336 0.0269 0.9256 0.9414 3
Vemurafenib C32 3.1600
uM
 72
hr
 775 688 0.0380 0.0274 0.8877 0.9276 3
PLX-4720 C32 3.1600
uM
 72
hr
 873 773 0.0437 0.0669 0.8855 0.8134 1
Selumetinib C32 3.1600
uM
 72
hr
 924 822 0.0445 0.0615 0.8896 0.8621 3
Selumetinib C32 3.1600
uM
 72
hr
 943 840 0.0450 0.0615 0.8908 0.8621 1
AZ-628 C32 1.0000
uM
 72
hr
 1409 1291 0.0515 0.0591 0.9163 0.8863 2
AZ-628 C32 1.0000
uM
 72
hr
 1155 1032 0.0537 0.0591 0.8935 0.8863 4
PLX-4720 C32 3.1600
uM
 72
hr
 856 729 0.0554 0.0669 0.8516 0.8134 3
AZ-628 C32 1.0000
uM
 72
hr
 1127 993 0.0585 0.0591 0.8811 0.8863 1
AZ-628 WM-115 3.1600
uM
 72
hr
 1146 960 0.0614 0.0874 0.8377 0.8202 1
AZ-628 C32 3.1600
uM
 48
hr
 1553 1419 0.0652 0.0749 0.9137 0.9051 4
AZ-628 WM-115 3.1600
uM
 72
hr
 1543 1340 0.0670 0.0874 0.8684 0.8202 2
Selumetinib C32 3.1600
uM
 72
hr
 1035 878 0.0685 0.0615 0.8483 0.8621 2
AZ-628 C32 3.1600
uM
 48
hr
 1609 1466 0.0696 0.0749 0.9111 0.9051 1
Vemurafenib MMAC-SF 3.1600
uM
 72
hr
 874 626 0.0721 0.0882 0.7163 0.6920 1
AZ-628 C32 1.0000
uM
 72
hr
 1138 972 0.0725 0.0591 0.8541 0.8863 3
Vemurafenib MMAC-SF 3.1600
uM
 72
hr
 931 655 0.0803 0.0882 0.7035 0.6920 4
AZ-628 C32 3.1600
uM
 48
hr
 1579 1414 0.0803 0.0749 0.8955 0.9051 3
Selumetinib C32 1.0000
uM
 72
hr
 1001 816 0.0808 0.1124 0.8152 0.7591 1
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