Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | LOXIMVI | 0.1000 | uM | 72 | hr | 5644 | 3.1833 | 2.8615 | 0.0636 | 0.0607 | 4 | |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 72 | hr | 5466 | 3.1567 | 2.7256 | 0.0412 | 0.0438 | 1 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 5438 | 3.1375 | 2.9681 | 0.0421 | 0.0478 | 1 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 5374 | 3.1266 | 2.9681 | 0.0341 | 0.0478 | 3 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 5369 | 3.1019 | 2.9681 | 0.0408 | 0.0478 | 2 | |
| SB590885 | LOXIMVI | 0.1000 | uM | 72 | hr | 5389 | 3.0712 | 2.8615 | 0.0538 | 0.0607 | 2 | |
| SB590885 | LOXIMVI | 0.1000 | uM | 72 | hr | 5185 | 2.9748 | 2.8615 | 0.0474 | 0.0607 | 1 | |
| SB590885 | LOXIMVI | 0.0316 | uM | 72 | hr | 5535 | 2.9712 | 2.2122 | 0.1088 | 0.1352 | 3 | |
| Vemurafenib | LOXIMVI | 0.0100 | uM | 72 | hr | 5187 | 2.8929 | 1.9783 | 0.0740 | 0.1534 | 4 | |
| Vemurafenib | LOXIMVI | 0.1000 | uM | 72 | hr | 4893 | 2.8146 | 2.7256 | 0.0450 | 0.0438 | 3 | |
| Vemurafenib | LOXIMVI | 0.3160 | uM | 72 | hr | 4835 | 2.7664 | 2.3370 | 0.0501 | 0.0484 | 1 | |
| Vemurafenib | LOXIMVI | 0.0316 | uM | 72 | hr | 4764 | 2.7442 | 2.3897 | 0.0437 | 0.0537 | 3 | |
| SB590885 | LOXIMVI | 1.0000 | uM | 72 | hr | 4727 | 2.7267 | 2.3305 | 0.0423 | 0.0458 | 2 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 72 | hr | 4643 | 2.7026 | 2.4826 | 0.0336 | 0.0395 | 4 | |
| AZ-628 | LOXIMVI | 0.0100 | uM | 72 | hr | 4731 | 2.6948 | 1.9518 | 0.0543 | 0.1045 | 4 | |
| Vemurafenib | K2 | 0.1000 | uM | 24 | hr | 4584 | 6 | 2.6924 | 2.1002 | 0.0013 | 0.0017 | 1 |
| PLX-4720 | LOXIMVI | 0.0316 | uM | 72 | hr | 4778 | 2.6900 | 2.3076 | 0.0653 | 0.0740 | 3 | |
| AZ-628 | LOXIMVI | 0.0316 | uM | 72 | hr | 4569 | 2.6291 | 2.1825 | 0.0446 | 0.0405 | 4 | |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 72 | hr | 4496 | 2.5954 | 2.4826 | 0.0416 | 0.0395 | 3 | |
| Selumetinib | LOXIMVI | 0.0100 | uM | 72 | hr | 4625 | 2.5737 | 1.9337 | 0.0761 | 0.0676 | 4 | |
| SB590885 | K2 | 0.1000 | uM | 24 | hr | 4354 | 8 | 2.5560 | 2.0680 | 0.0018 | 0.0026 | 2 |
| PLX-4720 | LOXIMVI | 0.1000 | uM | 72 | hr | 4363 | 2.5297 | 2.4826 | 0.0374 | 0.0395 | 2 | |
| Vemurafenib | LOXIMVI | 0.3160 | uM | 72 | hr | 4408 | 2.5165 | 2.3370 | 0.0522 | 0.0484 | 3 | |
| SB590885 | LOXIMVI | 0.3160 | uM | 72 | hr | 4494 | 2.5062 | 2.9681 | 0.0741 | 0.0478 | 4 | |
| Vemurafenib | K2 | 0.0316 | uM | 24 | hr | 4239 | 7 | 2.4890 | 2.1662 | 0.0017 | 0.0026 | 1 |