Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SB590885 | K2 | 0.0316 | uM | 48 | hr | 3564 | 6 | 1.2985 | 1.3782 | 0.0017 | 0.0017 | 2 |
| Vemurafenib | K2 | 0.1000 | uM | 24 | hr | 4584 | 6 | 2.6924 | 2.1002 | 0.0013 | 0.0017 | 1 |
| SB590885 | K2 | 0.0316 | uM | 48 | hr | 3871 | 6 | 1.4105 | 1.3782 | 0.0016 | 0.0017 | 4 |
| Vemurafenib | K2 | 0.0316 | uM | 48 | hr | 3967 | 5 | 1.4459 | 1.3791 | 0.0013 | 0.0017 | 3 |
| Vemurafenib | K2 | 0.0316 | uM | 48 | hr | 3964 | 7 | 1.4441 | 1.3791 | 0.0018 | 0.0017 | 2 |
| Vemurafenib | K2 | 0.1000 | uM | 24 | hr | 2673 | 4 | 1.5697 | 2.1002 | 0.0015 | 0.0017 | 4 |
| Vemurafenib | K2 | 0.0316 | uM | 48 | hr | 3651 | 7 | 1.3299 | 1.3791 | 0.0019 | 0.0017 | 4 |
| Vemurafenib | K2 | 0.1000 | uM | 24 | hr | 3909 | 10 | 2.2931 | 2.1002 | 0.0026 | 0.0017 | 2 |
| Vemurafenib | K2 | 0.1000 | uM | 24 | hr | 3143 | 5 | 1.8455 | 2.1002 | 0.0016 | 0.0017 | 3 |
| SB590885 | K2 | 0.0316 | uM | 48 | hr | 4144 | 5 | 1.5105 | 1.3782 | 0.0012 | 0.0017 | 1 |
| Vemurafenib | K2 | 0.0316 | uM | 48 | hr | 3560 | 7 | 1.2966 | 1.3791 | 0.0020 | 0.0017 | 1 |
| SB590885 | K2 | 0.0316 | uM | 48 | hr | 3553 | 9 | 1.2934 | 1.3782 | 0.0025 | 0.0017 | 3 |
| SB590885 | K2 | 0.0032 | uM | 48 | hr | 4588 | 8 | 1.6714 | 1.5110 | 0.0017 | 0.0019 | 4 |
| SB590885 | K2 | 0.0032 | uM | 48 | hr | 4079 | 5 | 1.4868 | 1.5110 | 0.0012 | 0.0019 | 2 |
| SB590885 | K2 | 0.0032 | uM | 48 | hr | 3865 | 7 | 1.4079 | 1.5110 | 0.0018 | 0.0019 | 1 |
| SB590885 | K2 | 0.0032 | uM | 48 | hr | 4061 | 12 | 1.4777 | 1.5110 | 0.0030 | 0.0019 | 3 |
| PLX-4720 | K2 | 0.0316 | uM | 48 | hr | 2668 | 9 | 0.9704 | 1.1865 | 0.0034 | 0.0020 | 4 |
| PLX-4720 | K2 | 0.0316 | uM | 48 | hr | 3231 | 6 | 1.1769 | 1.1865 | 0.0019 | 0.0020 | 1 |
| PLX-4720 | K2 | 0.0316 | uM | 48 | hr | 3876 | 5 | 1.4127 | 1.1865 | 0.0013 | 0.0020 | 2 |
| PLX-4720 | K2 | 0.0316 | uM | 48 | hr | 3255 | 5 | 1.1861 | 1.1865 | 0.0015 | 0.0020 | 3 |
| PLX-4720 | K2 | 0.0100 | uM | 48 | hr | 3702 | 8 | 1.3481 | 1.2705 | 0.0022 | 0.0022 | 3 |
| SB590885 | K2 | 0.0316 | uM | 24 | hr | 3360 | 10 | 1.9702 | 1.8176 | 0.0030 | 0.0022 | 1 |
| SB590885 | K2 | 0.0316 | uM | 24 | hr | 3898 | 5 | 2.2896 | 1.8176 | 0.0013 | 0.0022 | 2 |
| PLX-4720 | K2 | 0.0100 | uM | 48 | hr | 3201 | 7 | 1.1656 | 1.2705 | 0.0022 | 0.0022 | 1 |
| SB590885 | K2 | 0.0316 | uM | 24 | hr | 2387 | 4 | 1.4015 | 1.8176 | 0.0017 | 0.0022 | 3 |