Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | K2 | 0.0100 | uM | 48 | hr | 3571 | 0 | 1.3032 | 1.2705 | 0.0000 | 0.0022 | 2 |
| PLX-4720 | K2 | 0.0032 | uM | 48 | hr | 3865 | 1 | 1.4101 | 1.3444 | 0.0003 | 0.0024 | 1 |
| Selumetinib | K2 | 0.0100 | uM | 24 | hr | 1521 | 1 | 0.8940 | 1.1449 | 0.0007 | 0.0032 | 3 |
| AZ-628 | K2 | 0.0316 | uM | 24 | hr | 3254 | 3 | 1.9120 | 1.5718 | 0.0009 | 0.0028 | 1 |
| K2 | 0.0000 | uM | 48 | hr | 3568 | 4 | 1.3007 | 0.0011 | 1 | |||
| K2 | 0.0000 | uM | 48 | hr | 3670 | 4 | 1.3379 | 0.0011 | 1 | |||
| SB590885 | K2 | 0.0032 | uM | 48 | hr | 4079 | 5 | 1.4868 | 1.5110 | 0.0012 | 0.0019 | 2 |
| SB590885 | K2 | 0.0316 | uM | 48 | hr | 4144 | 5 | 1.5105 | 1.3782 | 0.0012 | 0.0017 | 1 |
| SB590885 | K2 | 0.0316 | uM | 24 | hr | 3898 | 5 | 2.2896 | 1.8176 | 0.0013 | 0.0022 | 2 |
| K2 | 0.0000 | uM | 24 | hr | 743 | 1 | 0.4364 | 0.0013 | 4 | |||
| Vemurafenib | K2 | 0.1000 | uM | 48 | hr | 3718 | 5 | 1.3550 | 1.4312 | 0.0013 | 0.0023 | 1 |
| Vemurafenib | K2 | 0.0316 | uM | 48 | hr | 3967 | 5 | 1.4459 | 1.3791 | 0.0013 | 0.0017 | 3 |
| PLX-4720 | K2 | 0.0316 | uM | 48 | hr | 3876 | 5 | 1.4127 | 1.1865 | 0.0013 | 0.0020 | 2 |
| Vemurafenib | K2 | 0.1000 | uM | 24 | hr | 4584 | 6 | 2.6924 | 2.1002 | 0.0013 | 0.0017 | 1 |
| SB590885 | K2 | 0.0100 | uM | 24 | hr | 3664 | 5 | 2.1520 | 1.7957 | 0.0014 | 0.0024 | 1 |
| K2 | 0.0000 | uM | 48 | hr | 4249 | 6 | 1.5485 | 0.0014 | 2 | |||
| AZ-628 | K2 | 0.0100 | uM | 48 | hr | 2849 | 4 | 1.0383 | 1.0336 | 0.0014 | 0.0030 | 1 |
| Vemurafenib | K2 | 0.1000 | uM | 24 | hr | 2673 | 4 | 1.5697 | 2.1002 | 0.0015 | 0.0017 | 4 |
| AZ-628 | K2 | 0.0032 | uM | 48 | hr | 3396 | 5 | 1.2375 | 1.1976 | 0.0015 | 0.0026 | 2 |
| Vemurafenib | K2 | 0.0100 | uM | 48 | hr | 4070 | 6 | 1.4831 | 1.3424 | 0.0015 | 0.0026 | 3 |
| Selumetinib | K2 | 0.0032 | uM | 48 | hr | 3377 | 5 | 1.2306 | 1.1652 | 0.0015 | 0.0027 | 2 |
| PLX-4720 | K2 | 0.0316 | uM | 48 | hr | 3255 | 5 | 1.1861 | 1.1865 | 0.0015 | 0.0020 | 3 |
| SB590885 | K2 | 0.0100 | uM | 48 | hr | 3901 | 6 | 1.4215 | 1.3746 | 0.0015 | 0.0028 | 1 |
| Selumetinib | K2 | 0.0316 | uM | 24 | hr | 1941 | 3 | 1.1398 | 1.0203 | 0.0015 | 0.0045 | 1 |
| Vemurafenib | K2 | 0.0032 | uM | 48 | hr | 3821 | 6 | 1.3923 | 1.4412 | 0.0016 | 0.0031 | 1 |