Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib RVH-421 0.0100
uM
 72
hr
 9833 326 1.0894 0.9881 0.0332 0.0321 2
RVH-421 0.0000
uM
 72
hr
 9811 389 1.0797 0.0396 1
PLX-4720 RVH-421 0.0316
uM
 72
hr
 9777 344 1.0809 1.0084 0.0352 0.0338 2
RVH-421 0.0000
uM
 72
hr
 9682 354 1.0689 0.0366 3
RVH-421 0.0000
uM
 72
hr
 9644 315 1.0690 0.0327 1
Selumetinib RVH-421 0.0032
uM
 72
hr
 9540 343 1.0539 1.0141 0.0360 0.0328 4
PLX-4720 RVH-421 0.0100
uM
 72
hr
 9529 333 1.0538 1.0312 0.0349 0.0350 2
RVH-421 0.0000
uM
 72
hr
 9484 344 1.0473 0.0363 2
Vemurafenib RVH-421 0.0316
uM
 72
hr
 9475 331 1.0478 0.9594 0.0349 0.0341 1
RVH-421 0.0000
uM
 72
hr
 9463 329 1.0467 0.0348 3
Vemurafenib RVH-421 0.0100
uM
 72
hr
 9463 361 1.0430 1.0156 0.0381 0.0343 2
PLX-4720 RVH-421 0.0100
uM
 72
hr
 9431 308 1.0454 1.0312 0.0327 0.0350 4
Selumetinib RVH-421 0.0032
uM
 72
hr
 9411 281 1.0462 1.0141 0.0299 0.0328 2
RVH-421 0.0000
uM
 72
hr
 9409 307 1.0430 0.0326 4
Vemurafenib RVH-421 0.0100
uM
 72
hr
 9386 311 1.0399 1.0156 0.0331 0.0343 4
RVH-421 0.0000
uM
 72
hr
 9372 401 1.0280 0.0428 1
RVH-421 0.0000
uM
 72
hr
 9350 519 1.0119 0.0555 4
SB590885 RVH-421 0.0032
uM
 72
hr
 9340 339 1.0314 0.9834 0.0363 0.0342 4
RVH-421 0.0000
uM
 72
hr
 9307 342 1.0273 0.0367 2
RVH-421 0.0000
uM
 72
hr
 9303 373 1.0233 0.0401 1
AZ-628 RVH-421 0.0032
uM
 72
hr
 9263 338 1.0227 0.9565 0.0365 0.0338 2
RVH-421 0.0000
uM
 72
hr
 9256 343 1.0213 0.0371 4
Selumetinib RVH-421 0.0032
uM
 72
hr
 9255 282 1.0282 1.0141 0.0305 0.0328 1
RVH-421 0.0000
uM
 72
hr
 9253 347 1.0205 0.0375 3
RVH-421 0.0000
uM
 72
hr
 9252 333 1.0220 0.0360 3
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