Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
AZ-628 C32 3.1600
uM
 48
hr
 1739 1565 0.0847 0.0749 0.8999 0.9051 2
AZ-628 C32 3.1600
uM
 48
hr
 1609 1466 0.0696 0.0749 0.9111 0.9051 1
Vemurafenib C32 3.1600
uM
 48
hr
 1677 1429 0.1207 0.1016 0.8521 0.8624 4
AZ-628 C32 3.1600
uM
 48
hr
 1553 1419 0.0652 0.0749 0.9137 0.9051 4
AZ-628 C32 3.1600
uM
 48
hr
 1579 1414 0.0803 0.0749 0.8955 0.9051 3
Selumetinib C32 3.1600
uM
 48
hr
 1702 1393 0.1504 0.1270 0.8185 0.8303 4
AZ-628 WM-115 3.1600
uM
 72
hr
 1543 1340 0.0670 0.0874 0.8684 0.8202 2
Vemurafenib C32 3.1600
uM
 48
hr
 1499 1332 0.0813 0.1016 0.8886 0.8624 1
Selumetinib C32 3.1600
uM
 48
hr
 1550 1314 0.1148 0.1270 0.8477 0.8303 2
Vemurafenib C32 3.1600
uM
 48
hr
 1537 1306 0.1124 0.1016 0.8497 0.8624 3
AZ-628 C32 1.0000
uM
 72
hr
 1409 1291 0.0515 0.0591 0.9163 0.8863 2
AZ-628 WM-115 3.1600
uM
 72
hr
 1633 1278 0.1171 0.0874 0.7826 0.8202 4
AZ-628 C32 1.0000
uM
 48
hr
 1504 1277 0.1105 0.1086 0.8491 0.8467 1
AZ-628 C32 1.0000
uM
 48
hr
 1468 1265 0.0988 0.1086 0.8617 0.8467 3
AZ-628 C32 1.0000
uM
 48
hr
 1469 1230 0.1163 0.1086 0.8373 0.8467 4
Selumetinib C32 3.1600
uM
 48
hr
 1464 1224 0.1168 0.1270 0.8361 0.8303 1
PLX-4720 C32 3.1600
uM
 48
hr
 1599 1210 0.1893 0.1550 0.7567 0.7840 4
PLX-4720 C32 3.1600
uM
 48
hr
 1504 1209 0.1435 0.1550 0.8039 0.7840 1
AZ-628 WM-115 3.1600
uM
 72
hr
 1520 1204 0.1042 0.0874 0.7921 0.8202 3
Selumetinib C32 3.1600
uM
 48
hr
 1431 1172 0.1260 0.1270 0.8190 0.8303 3
AZ-628 C32 1.0000
uM
 48
hr
 1387 1163 0.1090 0.1086 0.8385 0.8467 2
AZ-628 K2 3.1600
uM
 48
hr
 3215 1154 0.7522 0.5330 0.3589 0.3577 2
Vemurafenib C32 3.1600
uM
 48
hr
 1342 1153 0.0920 0.1016 0.8592 0.8624 2
Selumetinib C32 1.0000
uM
 48
hr
 1891 1111 0.3795 0.3220 0.5875 0.5982 4
PLX-4720 C32 3.1600
uM
 48
hr
 1443 1101 0.1664 0.1550 0.7630 0.7840 3
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