Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PLX-4720 | C32 | 3.1600 | uM | 48 | hr | 1443 | 1101 | 0.1664 | 0.1550 | 0.7630 | 0.7840 | 3 |
| PLX-4720 | C32 | 3.1600 | uM | 72 | hr | 856 | 729 | 0.0554 | 0.0669 | 0.8516 | 0.8134 | 3 |
| PLX-4720 | C32 | 3.1600 | uM | 24 | hr | 1770 | 516 | 0.7250 | 0.6928 | 0.2915 | 0.2905 | 1 |
| PLX-4720 | C32 | 3.1600 | uM | 48 | hr | 1321 | 1073 | 0.1207 | 0.1550 | 0.8123 | 0.7840 | 2 |
| PLX-4720 | C32 | 3.1600 | uM | 48 | hr | 1599 | 1210 | 0.1893 | 0.1550 | 0.7567 | 0.7840 | 4 |
| PLX-4720 | C32 | 3.1600 | uM | 72 | hr | 820 | 631 | 0.0825 | 0.0669 | 0.7695 | 0.8134 | 2 |
| SB590885 | C32 | 3.1600 | uM | 72 | hr | 990 | 497 | 0.2153 | 0.2092 | 0.5020 | 0.5417 | 4 |
| SB590885 | C32 | 3.1600 | uM | 72 | hr | 1142 | 655 | 0.2126 | 0.2092 | 0.5736 | 0.5417 | 1 |
| PLX-4720 | C32 | 3.1600 | uM | 24 | hr | 1520 | 387 | 0.6551 | 0.6928 | 0.2546 | 0.2905 | 3 |
| PLX-4720 | C32 | 3.1600 | uM | 48 | hr | 1504 | 1209 | 0.1435 | 0.1550 | 0.8039 | 0.7840 | 1 |
| SB590885 | C32 | 3.1600 | uM | 72 | hr | 1083 | 633 | 0.1965 | 0.2092 | 0.5845 | 0.5417 | 3 |
| SB590885 | C32 | 3.1600 | uM | 48 | hr | 1909 | 958 | 0.4627 | 0.3996 | 0.5018 | 0.5238 | 4 |
| SB590885 | C32 | 3.1600 | uM | 72 | hr | 987 | 500 | 0.2126 | 0.2092 | 0.5066 | 0.5417 | 2 |
| PLX-4720 | C32 | 3.1600 | uM | 72 | hr | 873 | 773 | 0.0437 | 0.0669 | 0.8855 | 0.8134 | 1 |
| SB590885 | C32 | 3.1600 | uM | 24 | hr | 1844 | 487 | 0.7846 | 0.7788 | 0.2641 | 0.2708 | 3 |
| SB590885 | C32 | 3.1600 | uM | 48 | hr | 1545 | 846 | 0.3401 | 0.3996 | 0.5476 | 0.5238 | 2 |
| SB590885 | C32 | 3.1600 | uM | 24 | hr | 1897 | 517 | 0.7979 | 0.7788 | 0.2725 | 0.2708 | 2 |
| SB590885 | C32 | 3.1600 | uM | 24 | hr | 1858 | 507 | 0.7811 | 0.7788 | 0.2729 | 0.2708 | 1 |
| SB590885 | C32 | 3.1600 | uM | 48 | hr | 1569 | 840 | 0.3547 | 0.3996 | 0.5354 | 0.5238 | 1 |
| PLX-4720 | C32 | 3.1600 | uM | 24 | hr | 1777 | 592 | 0.6851 | 0.6928 | 0.3332 | 0.2905 | 2 |
| SB590885 | C32 | 3.1600 | uM | 24 | hr | 1790 | 490 | 0.7516 | 0.7788 | 0.2737 | 0.2708 | 4 |
| PLX-4720 | C32 | 3.1600 | uM | 24 | hr | 1702 | 481 | 0.7059 | 0.6928 | 0.2826 | 0.2905 | 4 |
| SB590885 | C32 | 3.1600 | uM | 48 | hr | 1850 | 944 | 0.4408 | 0.3996 | 0.5103 | 0.5238 | 3 |
| AZ-628 | C32 | 3.1600 | uM | 24 | hr | 2015 | 456 | 0.9014 | 0.8769 | 0.2263 | 0.2397 | 1 |
| PLX-4720 | C32 | 3.1600 | uM | 72 | hr | 778 | 581 | 0.0860 | 0.0669 | 0.7468 | 0.8134 | 4 |