Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 7193.0 | 18525.7 | 2822.7 | 0.5 | 0.411 | 0.388 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 6542.0 | 18525.7 | 2822.7 | 0.5 | 0.363 | 0.353 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 6598.0 | 18525.7 | 2822.7 | 0.5 | 0.367 | 0.356 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 3.1623 | 5883.0 | 18525.7 | 2822.7 | 0.5 | 0.311 | 0.318 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 10.0 | 4995.0 | 18525.7 | 2822.7 | 1.0 | 0.234 | 0.270 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 10.0 | 4814.0 | 18525.7 | 2822.7 | 1.0 | 0.217 | 0.260 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 10.0 | 4351.0 | 18525.7 | 2822.7 | 1.0 | 0.173 | 0.235 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 2 | 72 | 10.0 | 4279.0 | 18525.7 | 2822.7 | 1.0 | 0.166 | 0.231 | 2.714 | HCC1806 Torin1 0 2 |
| HCC1806 | Torin1 | 3 | 72 | 0.001 | 13987.0 | 14413.7 | 2222.1 | -3.0 | 0.978 | 0.970 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.001 | 13345.0 | 14413.7 | 2222.1 | -3.0 | 0.944 | 0.926 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.001 | 13689.0 | 14413.7 | 2222.1 | -3.0 | 0.962 | 0.950 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.001 | 14600.0 | 14413.7 | 2222.1 | -3.0 | 1.010 | 1.010 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0032 | 14350.0 | 14413.7 | 2222.1 | -2.49 | 0.997 | 0.996 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0032 | 13025.0 | 14413.7 | 2222.1 | -2.49 | 0.926 | 0.904 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0032 | 15502.0 | 14413.7 | 2222.1 | -2.49 | 1.050 | 1.080 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0032 | 14493.0 | 14413.7 | 2222.1 | -2.49 | 1.000 | 1.010 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.01 | 14912.0 | 14413.7 | 2222.1 | -2.0 | 1.030 | 1.030 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.01 | 13941.0 | 14413.7 | 2222.1 | -2.0 | 0.975 | 0.967 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.01 | 13262.0 | 14413.7 | 2222.1 | -2.0 | 0.939 | 0.920 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.01 | 14292.0 | 14413.7 | 2222.1 | -2.0 | 0.994 | 0.992 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0316 | 12683.0 | 14413.7 | 2222.1 | -1.5 | 0.907 | 0.880 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0316 | 10876.0 | 14413.7 | 2222.1 | -1.5 | 0.802 | 0.755 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0316 | 11727.0 | 14413.7 | 2222.1 | -1.5 | 0.853 | 0.814 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.0316 | 13086.0 | 14413.7 | 2222.1 | -1.5 | 0.930 | 0.908 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.1 | 9360.0 | 14413.7 | 2222.1 | -1.0 | 0.704 | 0.649 | 2.697 | HCC1806 Torin1 0 3 |