Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1544.0 | 17793.8 | 2895.7 | 0.5 | -0.213 | 0.087 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1411.0 | 17793.8 | 2895.7 | 0.5 | -0.240 | 0.079 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1281.0 | 17793.8 | 2895.7 | 0.5 | -0.268 | 0.072 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 3.1623 | 1264.0 | 17793.8 | 2895.7 | 0.5 | -0.271 | 0.071 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 10.0 | 370.0 | 17793.8 | 2895.7 | 1.0 | -0.544 | 0.021 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 10.0 | 309.0 | 17793.8 | 2895.7 | 1.0 | -0.574 | 0.017 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 10.0 | 280.0 | 17793.8 | 2895.7 | 1.0 | -0.590 | 0.016 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 10.0 | 237.0 | 17793.8 | 2895.7 | 1.0 | -0.615 | 0.013 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.001 | 17811.0 | 18525.7 | 2822.7 | -3.0 | 0.971 | 0.961 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.001 | 17565.0 | 18525.7 | 2822.7 | -3.0 | 0.961 | 0.948 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.001 | 18028.0 | 18525.7 | 2822.7 | -3.0 | 0.980 | 0.973 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.001 | 17975.0 | 18525.7 | 2822.7 | -3.0 | 0.978 | 0.970 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0032 | 17768.0 | 18525.7 | 2822.7 | -2.49 | 0.969 | 0.959 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0032 | 16899.0 | 18525.7 | 2822.7 | -2.49 | 0.933 | 0.912 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0032 | 19663.0 | 18525.7 | 2822.7 | -2.49 | 1.040 | 1.060 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0032 | 19439.0 | 18525.7 | 2822.7 | -2.49 | 1.040 | 1.050 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.01 | 18526.0 | 18525.7 | 2822.7 | -2.0 | 1.000 | 1.000 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.01 | 18184.0 | 18525.7 | 2822.7 | -2.0 | 0.986 | 0.982 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.01 | 17901.0 | 18525.7 | 2822.7 | -2.0 | 0.975 | 0.966 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.01 | 19102.0 | 18525.7 | 2822.7 | -2.0 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0316 | 17584.0 | 18525.7 | 2822.7 | -1.5 | 0.962 | 0.949 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0316 | 19080.0 | 18525.7 | 2822.7 | -1.5 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0316 | 18526.0 | 18525.7 | 2822.7 | -1.5 | 1.000 | 1.000 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.0316 | 19036.0 | 18525.7 | 2822.7 | -1.5 | 1.020 | 1.030 | 2.714 | HCC1806 QL-XII-47 0 2 |
| HCC1806 | QL-XII-47 | 2 | 72 | 0.1 | 18367.0 | 18525.7 | 2822.7 | -1.0 | 0.994 | 0.991 | 2.714 | HCC1806 QL-XII-47 0 2 |