Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin1 | 3 | 72 | 0.1 | 8612.0 | 14413.7 | 2222.1 | -1.0 | 0.652 | 0.597 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.1 | 9122.0 | 14413.7 | 2222.1 | -1.0 | 0.688 | 0.633 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.1 | 8279.0 | 14413.7 | 2222.1 | -1.0 | 0.628 | 0.574 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.3162 | 6524.0 | 14413.7 | 2222.1 | -0.5 | 0.491 | 0.453 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.3162 | 6320.0 | 14413.7 | 2222.1 | -0.5 | 0.473 | 0.438 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.3162 | 6543.0 | 14413.7 | 2222.1 | -0.5 | 0.492 | 0.454 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 0.3162 | 7125.0 | 14413.7 | 2222.1 | -0.5 | 0.540 | 0.494 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 1.0 | 5488.0 | 14413.7 | 2222.1 | 0.0 | 0.398 | 0.381 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 1.0 | 5711.0 | 14413.7 | 2222.1 | 0.0 | 0.419 | 0.396 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 1.0 | 5821.0 | 14413.7 | 2222.1 | 0.0 | 0.429 | 0.404 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 1.0 | 5587.0 | 14413.7 | 2222.1 | 0.0 | 0.407 | 0.388 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 3.1623 | 4860.0 | 14413.7 | 2222.1 | 0.5 | 0.337 | 0.337 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 3.1623 | 4271.0 | 14413.7 | 2222.1 | 0.5 | 0.274 | 0.296 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 3.1623 | 4418.0 | 14413.7 | 2222.1 | 0.5 | 0.290 | 0.307 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 3.1623 | 4517.0 | 14413.7 | 2222.1 | 0.5 | 0.301 | 0.313 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 10.0 | 3499.0 | 14413.7 | 2222.1 | 1.0 | 0.183 | 0.243 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 10.0 | 3251.0 | 14413.7 | 2222.1 | 1.0 | 0.152 | 0.226 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 10.0 | 3331.0 | 14413.7 | 2222.1 | 1.0 | 0.162 | 0.231 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin1 | 3 | 72 | 10.0 | 2726.0 | 14413.7 | 2222.1 | 1.0 | 0.079 | 0.189 | 2.697 | HCC1806 Torin1 0 3 |
| HCC1806 | Torin2 | 1 | 72 | 0.001 | 17499.0 | 17793.8 | 2895.7 | -3.0 | 0.987 | 0.983 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 0.001 | 17283.0 | 17793.8 | 2895.7 | -3.0 | 0.978 | 0.971 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 0.001 | 17714.0 | 17793.8 | 2895.7 | -3.0 | 0.997 | 0.996 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 0.001 | 17427.0 | 17793.8 | 2895.7 | -3.0 | 0.984 | 0.979 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 0.0032 | 17353.0 | 17793.8 | 2895.7 | -2.49 | 0.981 | 0.975 | 2.619 | HCC1806 Torin2 0 1 |
| HCC1806 | Torin2 | 1 | 72 | 0.0032 | 16347.0 | 17793.8 | 2895.7 | -2.49 | 0.936 | 0.919 | 2.619 | HCC1806 Torin2 0 1 |