Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2571.0 | 6533.6 | 1943.1 | 0.5 | 0.174 | 0.394 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2404.0 | 6533.6 | 1943.1 | 0.5 | 0.129 | 0.368 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2477.0 | 6533.6 | 1943.1 | 0.5 | 0.149 | 0.379 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 3.1623 | 2446.0 | 6533.6 | 1943.1 | 0.5 | 0.141 | 0.374 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2318.0 | 6533.6 | 1943.1 | 1.0 | 0.106 | 0.355 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2127.0 | 6533.6 | 1943.1 | 1.0 | 0.053 | 0.326 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2061.0 | 6533.6 | 1943.1 | 1.0 | 0.034 | 0.315 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | AZD8055 | 3 | 72 | 10.0 | 2011.0 | 6533.6 | 1943.1 | 1.0 | 0.020 | 0.308 | 1.750 | HCC70 AZD8055 0 3 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7489.0 | 7580.8 | 2503.8 | -3.0 | 0.985 | 0.988 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7088.0 | 7580.8 | 2503.8 | -3.0 | 0.918 | 0.935 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7426.0 | 7580.8 | 2503.8 | -3.0 | 0.974 | 0.980 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.001 | 7090.0 | 7580.8 | 2503.8 | -3.0 | 0.918 | 0.935 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0032 | 6984.0 | 7580.8 | 2503.8 | -2.49 | 0.900 | 0.921 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0032 | 7570.0 | 7580.8 | 2503.8 | -2.49 | 0.998 | 0.999 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0032 | 7230.0 | 7580.8 | 2503.8 | -2.49 | 0.942 | 0.954 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0032 | 7635.0 | 7580.8 | 2503.8 | -2.49 | 1.010 | 1.010 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.01 | 6912.0 | 7580.8 | 2503.8 | -2.0 | 0.888 | 0.912 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.01 | 6752.0 | 7580.8 | 2503.8 | -2.0 | 0.860 | 0.891 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.01 | 6960.0 | 7580.8 | 2503.8 | -2.0 | 0.896 | 0.918 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.01 | 7002.0 | 7580.8 | 2503.8 | -2.0 | 0.903 | 0.924 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0316 | 5803.0 | 7580.8 | 2503.8 | -1.5 | 0.692 | 0.765 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0316 | 5947.0 | 7580.8 | 2503.8 | -1.5 | 0.718 | 0.784 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0316 | 6261.0 | 7580.8 | 2503.8 | -1.5 | 0.774 | 0.826 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.0316 | 6177.0 | 7580.8 | 2503.8 | -1.5 | 0.759 | 0.815 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 4416.0 | 7580.8 | 2503.8 | -1.0 | 0.426 | 0.583 | 1.598 | HCC70 QL-IV-100 0 1 |