Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 4909.0 | 7580.8 | 2503.8 | -1.0 | 0.524 | 0.648 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 5099.0 | 7580.8 | 2503.8 | -1.0 | 0.561 | 0.673 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.1 | 4657.0 | 7580.8 | 2503.8 | -1.0 | 0.474 | 0.614 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3727.0 | 7580.8 | 2503.8 | -0.5 | 0.283 | 0.492 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3706.0 | 7580.8 | 2503.8 | -0.5 | 0.278 | 0.489 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3705.0 | 7580.8 | 2503.8 | -0.5 | 0.278 | 0.489 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 0.3162 | 3920.0 | 7580.8 | 2503.8 | -0.5 | 0.324 | 0.517 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1611.0 | 7580.8 | 2503.8 | 0.0 | -0.241 | 0.213 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1630.0 | 7580.8 | 2503.8 | 0.0 | -0.236 | 0.215 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1549.0 | 7580.8 | 2503.8 | 0.0 | -0.260 | 0.204 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 1.0 | 1415.0 | 7580.8 | 2503.8 | 0.0 | -0.300 | 0.187 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 642.0 | 7580.8 | 2503.8 | 0.5 | -0.573 | 0.085 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 561.0 | 7580.8 | 2503.8 | 0.5 | -0.608 | 0.074 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 529.0 | 7580.8 | 2503.8 | 0.5 | -0.622 | 0.070 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 3.1623 | 686.0 | 7580.8 | 2503.8 | 0.5 | -0.555 | 0.091 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 10.0 | 343.0 | 7580.8 | 2503.8 | 1.0 | -0.712 | 0.045 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 10.0 | 366.0 | 7580.8 | 2503.8 | 1.0 | -0.700 | 0.048 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 10.0 | 335.0 | 7580.8 | 2503.8 | 1.0 | -0.716 | 0.044 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 1 | 72 | 10.0 | 321.0 | 7580.8 | 2503.8 | 1.0 | -0.723 | 0.042 | 1.598 | HCC70 QL-IV-100 0 1 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6750.0 | 7167.9 | 2409.0 | -3.0 | 0.925 | 0.942 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6268.0 | 7167.9 | 2409.0 | -3.0 | 0.837 | 0.874 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6210.0 | 7167.9 | 2409.0 | -3.0 | 0.826 | 0.866 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.001 | 6454.0 | 7167.9 | 2409.0 | -3.0 | 0.871 | 0.900 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0032 | 6850.0 | 7167.9 | 2409.0 | -2.49 | 0.943 | 0.956 | 1.573 | HCC70 QL-IV-100 0 2 |
| HCC70 | QL-IV-100 | 2 | 72 | 0.0032 | 7367.0 | 7167.9 | 2409.0 | -2.49 | 1.040 | 1.030 | 1.573 | HCC70 QL-IV-100 0 2 |