Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-73 | 1 | 72 | 1.0 | 3967.0 | 7580.8 | 2503.8 | 0.0 | 0.334 | 0.523 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 1.0 | 4634.0 | 7580.8 | 2503.8 | 0.0 | 0.470 | 0.611 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 3.1623 | 2022.0 | 7580.8 | 2503.8 | 0.5 | -0.125 | 0.267 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 3.1623 | 1903.0 | 7580.8 | 2503.8 | 0.5 | -0.158 | 0.251 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 3.1623 | 1816.0 | 7580.8 | 2503.8 | 0.5 | -0.182 | 0.240 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 3.1623 | 2031.0 | 7580.8 | 2503.8 | 0.5 | -0.123 | 0.268 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 647.0 | 7580.8 | 2503.8 | 1.0 | -0.571 | 0.085 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 619.0 | 7580.8 | 2503.8 | 1.0 | -0.583 | 0.082 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 753.0 | 7580.8 | 2503.8 | 1.0 | -0.528 | 0.099 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 1 | 72 | 10.0 | 703.0 | 7580.8 | 2503.8 | 1.0 | -0.548 | 0.093 | 1.598 | HCC70 QL-V-73 0 1 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6883.0 | 7167.9 | 2409.0 | -3.0 | 0.949 | 0.960 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6280.0 | 7167.9 | 2409.0 | -3.0 | 0.839 | 0.876 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 6894.0 | 7167.9 | 2409.0 | -3.0 | 0.951 | 0.962 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.001 | 7041.0 | 7167.9 | 2409.0 | -3.0 | 0.977 | 0.982 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.0032 | 7021.0 | 7167.9 | 2409.0 | -2.49 | 0.974 | 0.980 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.0032 | 6544.0 | 7167.9 | 2409.0 | -2.49 | 0.888 | 0.913 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.0032 | 6418.0 | 7167.9 | 2409.0 | -2.49 | 0.864 | 0.895 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.0032 | 7160.0 | 7167.9 | 2409.0 | -2.49 | 0.999 | 0.999 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.01 | 6514.0 | 7167.9 | 2409.0 | -2.0 | 0.882 | 0.909 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.01 | 7066.0 | 7167.9 | 2409.0 | -2.0 | 0.982 | 0.986 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.01 | 7627.0 | 7167.9 | 2409.0 | -2.0 | 1.080 | 1.060 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.01 | 6304.0 | 7167.9 | 2409.0 | -2.0 | 0.843 | 0.879 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.0316 | 6108.0 | 7167.9 | 2409.0 | -1.5 | 0.807 | 0.852 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.0316 | 6427.0 | 7167.9 | 2409.0 | -1.5 | 0.866 | 0.897 | 1.573 | HCC70 QL-V-73 0 2 |
| HCC70 | QL-V-73 | 2 | 72 | 0.0316 | 6465.0 | 7167.9 | 2409.0 | -1.5 | 0.873 | 0.902 | 1.573 | HCC70 QL-V-73 0 2 |