Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-73 | 3 | 72 | 3.1623 | 1668.0 | 6533.6 | 1943.1 | 0.5 | -0.084 | 0.255 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 3.1623 | 1494.0 | 6533.6 | 1943.1 | 0.5 | -0.139 | 0.229 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 3.1623 | 1762.0 | 6533.6 | 1943.1 | 0.5 | -0.054 | 0.270 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 537.0 | 6533.6 | 1943.1 | 1.0 | -0.521 | 0.082 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 460.0 | 6533.6 | 1943.1 | 1.0 | -0.561 | 0.070 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 554.0 | 6533.6 | 1943.1 | 1.0 | -0.512 | 0.085 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 10.0 | 547.0 | 6533.6 | 1943.1 | 1.0 | -0.515 | 0.084 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7695.0 | 7580.8 | 2503.8 | -3.0 | 1.020 | 1.020 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7181.0 | 7580.8 | 2503.8 | -3.0 | 0.933 | 0.947 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7231.0 | 7580.8 | 2503.8 | -3.0 | 0.942 | 0.954 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.001 | 7422.0 | 7580.8 | 2503.8 | -3.0 | 0.974 | 0.979 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 7424.0 | 7580.8 | 2503.8 | -2.49 | 0.974 | 0.979 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 7410.0 | 7580.8 | 2503.8 | -2.49 | 0.972 | 0.977 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 6844.0 | 7580.8 | 2503.8 | -2.49 | 0.876 | 0.903 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0032 | 7700.0 | 7580.8 | 2503.8 | -2.49 | 1.020 | 1.020 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.01 | 8045.0 | 7580.8 | 2503.8 | -2.0 | 1.080 | 1.060 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.01 | 7869.0 | 7580.8 | 2503.8 | -2.0 | 1.050 | 1.040 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.01 | 7840.0 | 7580.8 | 2503.8 | -2.0 | 1.040 | 1.030 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.01 | 7651.0 | 7580.8 | 2503.8 | -2.0 | 1.010 | 1.010 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0316 | 6849.0 | 7580.8 | 2503.8 | -1.5 | 0.877 | 0.903 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0316 | 6587.0 | 7580.8 | 2503.8 | -1.5 | 0.832 | 0.869 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0316 | 6289.0 | 7580.8 | 2503.8 | -1.5 | 0.779 | 0.830 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.0316 | 7166.0 | 7580.8 | 2503.8 | -1.5 | 0.931 | 0.945 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.1 | 5531.0 | 7580.8 | 2503.8 | -1.0 | 0.642 | 0.730 | 1.598 | HCC70 QL-VI-86 0 1 |
| HCC70 | QL-VI-86 | 1 | 72 | 0.1 | 5640.0 | 7580.8 | 2503.8 | -1.0 | 0.662 | 0.744 | 1.598 | HCC70 QL-VI-86 0 1 |