Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-V-73 | 3 | 72 | 0.0032 | 6466.0 | 6533.6 | 1943.1 | -2.49 | 0.988 | 0.990 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0032 | 6606.0 | 6533.6 | 1943.1 | -2.49 | 1.010 | 1.010 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0032 | 6445.0 | 6533.6 | 1943.1 | -2.49 | 0.984 | 0.986 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0032 | 7126.0 | 6533.6 | 1943.1 | -2.49 | 1.100 | 1.090 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.01 | 6378.0 | 6533.6 | 1943.1 | -2.0 | 0.973 | 0.976 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.01 | 6014.0 | 6533.6 | 1943.1 | -2.0 | 0.907 | 0.920 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.01 | 7006.0 | 6533.6 | 1943.1 | -2.0 | 1.080 | 1.070 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.01 | 6728.0 | 6533.6 | 1943.1 | -2.0 | 1.030 | 1.030 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0316 | 6471.0 | 6533.6 | 1943.1 | -1.5 | 0.989 | 0.990 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0316 | 6300.0 | 6533.6 | 1943.1 | -1.5 | 0.959 | 0.964 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0316 | 6090.0 | 6533.6 | 1943.1 | -1.5 | 0.921 | 0.932 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.0316 | 6027.0 | 6533.6 | 1943.1 | -1.5 | 0.910 | 0.922 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.1 | 5539.0 | 6533.6 | 1943.1 | -1.0 | 0.820 | 0.848 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.1 | 5936.0 | 6533.6 | 1943.1 | -1.0 | 0.893 | 0.909 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.1 | 5901.0 | 6533.6 | 1943.1 | -1.0 | 0.887 | 0.903 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.1 | 5165.0 | 6533.6 | 1943.1 | -1.0 | 0.749 | 0.791 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.3162 | 5071.0 | 6533.6 | 1943.1 | -0.5 | 0.730 | 0.776 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.3162 | 4767.0 | 6533.6 | 1943.1 | -0.5 | 0.670 | 0.730 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.3162 | 4952.0 | 6533.6 | 1943.1 | -0.5 | 0.707 | 0.758 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 0.3162 | 5465.0 | 6533.6 | 1943.1 | -0.5 | 0.806 | 0.836 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3420.0 | 6533.6 | 1943.1 | 0.0 | 0.381 | 0.523 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3509.0 | 6533.6 | 1943.1 | 0.0 | 0.402 | 0.537 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3478.0 | 6533.6 | 1943.1 | 0.0 | 0.395 | 0.532 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 1.0 | 3820.0 | 6533.6 | 1943.1 | 0.0 | 0.472 | 0.585 | 1.750 | HCC70 QL-V-73 0 3 |
| HCC70 | QL-V-73 | 3 | 72 | 3.1623 | 1727.0 | 6533.6 | 1943.1 | 0.5 | -0.065 | 0.264 | 1.750 | HCC70 QL-V-73 0 3 |