Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-X-138 | 1 | 72 | 1.0 | 5688.0 | 7580.8 | 2503.8 | 0.0 | 0.671 | 0.750 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 3.1623 | 3678.0 | 7580.8 | 2503.8 | 0.5 | 0.272 | 0.485 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 3.1623 | 3290.0 | 7580.8 | 2503.8 | 0.5 | 0.186 | 0.434 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 3.1623 | 3514.0 | 7580.8 | 2503.8 | 0.5 | 0.236 | 0.464 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 3.1623 | 3279.0 | 7580.8 | 2503.8 | 0.5 | 0.184 | 0.433 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 10.0 | 1683.0 | 7580.8 | 2503.8 | 1.0 | -0.220 | 0.222 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 10.0 | 1705.0 | 7580.8 | 2503.8 | 1.0 | -0.214 | 0.225 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 10.0 | 1647.0 | 7580.8 | 2503.8 | 1.0 | -0.231 | 0.217 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 1 | 72 | 10.0 | 1794.0 | 7580.8 | 2503.8 | 1.0 | -0.188 | 0.237 | 1.598 | HCC70 QL-X-138 0 1 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7677.0 | 7167.9 | 2409.0 | -3.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7256.0 | 7167.9 | 2409.0 | -3.0 | 1.020 | 1.010 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 7670.0 | 7167.9 | 2409.0 | -3.0 | 1.090 | 1.070 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.001 | 8440.0 | 7167.9 | 2409.0 | -3.0 | 1.220 | 1.180 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 6819.0 | 7167.9 | 2409.0 | -2.49 | 0.938 | 0.951 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7121.0 | 7167.9 | 2409.0 | -2.49 | 0.992 | 0.993 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7844.0 | 7167.9 | 2409.0 | -2.49 | 1.120 | 1.090 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0032 | 7303.0 | 7167.9 | 2409.0 | -2.49 | 1.020 | 1.020 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7456.0 | 7167.9 | 2409.0 | -2.0 | 1.050 | 1.040 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7734.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7165.0 | 7167.9 | 2409.0 | -2.0 | 0.999 | 1.000 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.01 | 7762.0 | 7167.9 | 2409.0 | -2.0 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 7128.0 | 7167.9 | 2409.0 | -1.5 | 0.993 | 0.994 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 8133.0 | 7167.9 | 2409.0 | -1.5 | 1.170 | 1.130 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 7255.0 | 7167.9 | 2409.0 | -1.5 | 1.020 | 1.010 | 1.573 | HCC70 QL-X-138 0 2 |
| HCC70 | QL-X-138 | 2 | 72 | 0.0316 | 7762.0 | 7167.9 | 2409.0 | -1.5 | 1.100 | 1.080 | 1.573 | HCC70 QL-X-138 0 2 |