Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-61 | 1 | 72 | 0.3162 | 18260.0 | 17793.8 | 2895.7 | -0.5 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.3162 | 18960.0 | 17793.8 | 2895.7 | -0.5 | 1.050 | 1.070 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.3162 | 18130.0 | 17793.8 | 2895.7 | -0.5 | 1.010 | 1.020 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.3162 | 19063.0 | 17793.8 | 2895.7 | -0.5 | 1.050 | 1.070 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 1.0 | 17589.0 | 17793.8 | 2895.7 | 0.0 | 0.991 | 0.988 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 1.0 | 18471.0 | 17793.8 | 2895.7 | 0.0 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 1.0 | 18424.0 | 17793.8 | 2895.7 | 0.0 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 1.0 | 18880.0 | 17793.8 | 2895.7 | 0.0 | 1.050 | 1.060 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 3.1623 | 16405.0 | 17793.8 | 2895.7 | 0.5 | 0.939 | 0.922 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 3.1623 | 16381.0 | 17793.8 | 2895.7 | 0.5 | 0.938 | 0.921 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 3.1623 | 16615.0 | 17793.8 | 2895.7 | 0.5 | 0.948 | 0.934 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 3.1623 | 17215.0 | 17793.8 | 2895.7 | 0.5 | 0.975 | 0.967 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 10.0 | 5550.0 | 17793.8 | 2895.7 | 1.0 | 0.282 | 0.312 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 10.0 | 7457.0 | 17793.8 | 2895.7 | 1.0 | 0.435 | 0.419 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 10.0 | 7813.0 | 17793.8 | 2895.7 | 1.0 | 0.461 | 0.439 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 10.0 | 7682.0 | 17793.8 | 2895.7 | 1.0 | 0.451 | 0.432 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.001 | 19576.0 | 18525.7 | 2822.7 | -3.0 | 1.040 | 1.060 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.001 | 18068.0 | 18525.7 | 2822.7 | -3.0 | 0.982 | 0.975 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.001 | 18744.0 | 18525.7 | 2822.7 | -3.0 | 1.010 | 1.010 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.001 | 18352.0 | 18525.7 | 2822.7 | -3.0 | 0.993 | 0.991 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0032 | 19588.0 | 18525.7 | 2822.7 | -2.49 | 1.040 | 1.060 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0032 | 18097.0 | 18525.7 | 2822.7 | -2.49 | 0.983 | 0.977 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0032 | 17807.0 | 18525.7 | 2822.7 | -2.49 | 0.971 | 0.961 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.0032 | 16768.0 | 18525.7 | 2822.7 | -2.49 | 0.928 | 0.905 | 2.714 | HCC1806 QL-XII-61 0 2 |
| HCC1806 | QL-XII-61 | 2 | 72 | 0.01 | 19558.0 | 18525.7 | 2822.7 | -2.0 | 1.040 | 1.060 | 2.714 | HCC1806 QL-XII-61 0 2 |