Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-47 | 3 | 72 | 3.1623 | 661.0 | 14413.7 | 2222.1 | 0.5 | -0.362 | 0.046 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 10.0 | 61.0 | 14413.7 | 2222.1 | 1.0 | -0.736 | 0.004 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 10.0 | 26.0 | 14413.7 | 2222.1 | 1.0 | -0.808 | 0.002 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 10.0 | 32.0 | 14413.7 | 2222.1 | 1.0 | -0.792 | 0.002 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-47 | 3 | 72 | 10.0 | 63.0 | 14413.7 | 2222.1 | 1.0 | -0.733 | 0.004 | 2.697 | HCC1806 QL-XII-47 0 3 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 18181.0 | 17793.8 | 2895.7 | -3.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 17153.0 | 17793.8 | 2895.7 | -3.0 | 0.972 | 0.964 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 18631.0 | 17793.8 | 2895.7 | -3.0 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.001 | 17822.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0032 | 18752.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0032 | 18586.0 | 17793.8 | 2895.7 | -2.49 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0032 | 16651.0 | 17793.8 | 2895.7 | -2.49 | 0.950 | 0.936 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0032 | 18275.0 | 17793.8 | 2895.7 | -2.49 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.01 | 18921.0 | 17793.8 | 2895.7 | -2.0 | 1.050 | 1.060 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.01 | 18010.0 | 17793.8 | 2895.7 | -2.0 | 1.010 | 1.010 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.01 | 18441.0 | 17793.8 | 2895.7 | -2.0 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.01 | 17266.0 | 17793.8 | 2895.7 | -2.0 | 0.977 | 0.970 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0316 | 17554.0 | 17793.8 | 2895.7 | -1.5 | 0.990 | 0.987 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0316 | 19318.0 | 17793.8 | 2895.7 | -1.5 | 1.060 | 1.090 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0316 | 18059.0 | 17793.8 | 2895.7 | -1.5 | 1.010 | 1.010 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.0316 | 18184.0 | 17793.8 | 2895.7 | -1.5 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.1 | 18647.0 | 17793.8 | 2895.7 | -1.0 | 1.040 | 1.050 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.1 | 18026.0 | 17793.8 | 2895.7 | -1.0 | 1.010 | 1.010 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.1 | 17091.0 | 17793.8 | 2895.7 | -1.0 | 0.969 | 0.961 | 2.619 | HCC1806 QL-XII-61 0 1 |
| HCC1806 | QL-XII-61 | 1 | 72 | 0.1 | 18044.0 | 17793.8 | 2895.7 | -1.0 | 1.010 | 1.010 | 2.619 | HCC1806 QL-XII-61 0 1 |