Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin2 | 2 | 72 | 0.3162 | 2180.0 | 18525.7 | 2822.7 | -0.5 | -0.091 | 0.118 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 0.3162 | 1931.0 | 18525.7 | 2822.7 | -0.5 | -0.131 | 0.104 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 0.3162 | 2645.0 | 18525.7 | 2822.7 | -0.5 | -0.024 | 0.143 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 0.3162 | 2342.0 | 18525.7 | 2822.7 | -0.5 | -0.067 | 0.126 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1166.0 | 18525.7 | 2822.7 | 0.0 | -0.278 | 0.063 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1211.0 | 18525.7 | 2822.7 | 0.0 | -0.268 | 0.065 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1071.0 | 18525.7 | 2822.7 | 0.0 | -0.300 | 0.058 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 1.0 | 1207.0 | 18525.7 | 2822.7 | 0.0 | -0.269 | 0.065 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1273.0 | 18525.7 | 2822.7 | 0.5 | -0.254 | 0.069 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1231.0 | 18525.7 | 2822.7 | 0.5 | -0.263 | 0.066 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1297.0 | 18525.7 | 2822.7 | 0.5 | -0.249 | 0.070 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 3.1623 | 1264.0 | 18525.7 | 2822.7 | 0.5 | -0.256 | 0.068 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 10.0 | 484.0 | 18525.7 | 2822.7 | 1.0 | -0.478 | 0.026 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 10.0 | 505.0 | 18525.7 | 2822.7 | 1.0 | -0.470 | 0.027 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 10.0 | 466.0 | 18525.7 | 2822.7 | 1.0 | -0.485 | 0.025 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 2 | 72 | 10.0 | 602.0 | 18525.7 | 2822.7 | 1.0 | -0.434 | 0.033 | 2.714 | HCC1806 Torin2 0 2 |
| HCC1806 | Torin2 | 3 | 72 | 0.001 | 14457.0 | 14413.7 | 2222.1 | -3.0 | 1.000 | 1.000 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.001 | 13883.0 | 14413.7 | 2222.1 | -3.0 | 0.972 | 0.963 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.001 | 13373.0 | 14413.7 | 2222.1 | -3.0 | 0.945 | 0.928 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.001 | 13362.0 | 14413.7 | 2222.1 | -3.0 | 0.945 | 0.927 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0032 | 14038.0 | 14413.7 | 2222.1 | -2.49 | 0.981 | 0.974 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0032 | 13523.0 | 14413.7 | 2222.1 | -2.49 | 0.953 | 0.938 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0032 | 13487.0 | 14413.7 | 2222.1 | -2.49 | 0.951 | 0.936 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0032 | 14775.0 | 14413.7 | 2222.1 | -2.49 | 1.020 | 1.030 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.01 | 12899.0 | 14413.7 | 2222.1 | -2.0 | 0.919 | 0.895 | 2.697 | HCC1806 Torin2 0 3 |