Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | Torin2 | 3 | 72 | 0.01 | 12397.0 | 14413.7 | 2222.1 | -2.0 | 0.891 | 0.860 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.01 | 13658.0 | 14413.7 | 2222.1 | -2.0 | 0.960 | 0.948 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.01 | 12602.0 | 14413.7 | 2222.1 | -2.0 | 0.903 | 0.874 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0316 | 9084.0 | 14413.7 | 2222.1 | -1.5 | 0.685 | 0.630 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0316 | 8563.0 | 14413.7 | 2222.1 | -1.5 | 0.649 | 0.594 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0316 | 7816.0 | 14413.7 | 2222.1 | -1.5 | 0.594 | 0.542 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.0316 | 9180.0 | 14413.7 | 2222.1 | -1.5 | 0.692 | 0.637 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.1 | 4827.0 | 14413.7 | 2222.1 | -1.0 | 0.333 | 0.335 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.1 | 4856.0 | 14413.7 | 2222.1 | -1.0 | 0.336 | 0.337 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.1 | 5010.0 | 14413.7 | 2222.1 | -1.0 | 0.352 | 0.348 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.1 | 5273.0 | 14413.7 | 2222.1 | -1.0 | 0.378 | 0.366 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.3162 | 1453.0 | 14413.7 | 2222.1 | -0.5 | -0.146 | 0.101 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.3162 | 1450.0 | 14413.7 | 2222.1 | -0.5 | -0.146 | 0.101 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.3162 | 1812.0 | 14413.7 | 2222.1 | -0.5 | -0.073 | 0.126 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 0.3162 | 1703.0 | 14413.7 | 2222.1 | -0.5 | -0.094 | 0.118 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 926.0 | 14413.7 | 2222.1 | 0.0 | -0.277 | 0.064 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 863.0 | 14413.7 | 2222.1 | 0.0 | -0.296 | 0.060 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 806.0 | 14413.7 | 2222.1 | 0.0 | -0.313 | 0.056 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 1.0 | 908.0 | 14413.7 | 2222.1 | 0.0 | -0.282 | 0.063 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 899.0 | 14413.7 | 2222.1 | 0.5 | -0.285 | 0.062 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 847.0 | 14413.7 | 2222.1 | 0.5 | -0.301 | 0.059 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 881.0 | 14413.7 | 2222.1 | 0.5 | -0.290 | 0.061 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 3.1623 | 821.0 | 14413.7 | 2222.1 | 0.5 | -0.309 | 0.057 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 10.0 | 222.0 | 14413.7 | 2222.1 | 1.0 | -0.574 | 0.015 | 2.697 | HCC1806 Torin2 0 3 |
| HCC1806 | Torin2 | 3 | 72 | 10.0 | 253.0 | 14413.7 | 2222.1 | 1.0 | -0.553 | 0.018 | 2.697 | HCC1806 Torin2 0 3 |