Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-47 | 1 | 72 | 0.001 | 17952.0 | 17793.8 | 2895.7 | -3.0 | 1.010 | 1.010 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0032 | 17765.0 | 17793.8 | 2895.7 | -2.49 | 0.999 | 0.998 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0032 | 18841.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.060 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0032 | 18790.0 | 17793.8 | 2895.7 | -2.49 | 1.040 | 1.060 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0032 | 18540.0 | 17793.8 | 2895.7 | -2.49 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.01 | 17453.0 | 17793.8 | 2895.7 | -2.0 | 0.985 | 0.981 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.01 | 17376.0 | 17793.8 | 2895.7 | -2.0 | 0.982 | 0.977 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.01 | 18203.0 | 17793.8 | 2895.7 | -2.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.01 | 18042.0 | 17793.8 | 2895.7 | -2.0 | 1.010 | 1.010 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0316 | 17454.0 | 17793.8 | 2895.7 | -1.5 | 0.985 | 0.981 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0316 | 18154.0 | 17793.8 | 2895.7 | -1.5 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0316 | 18483.0 | 17793.8 | 2895.7 | -1.5 | 1.030 | 1.040 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.0316 | 16955.0 | 17793.8 | 2895.7 | -1.5 | 0.963 | 0.953 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.1 | 17254.0 | 17793.8 | 2895.7 | -1.0 | 0.977 | 0.970 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.1 | 16932.0 | 17793.8 | 2895.7 | -1.0 | 0.962 | 0.952 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.1 | 18288.0 | 17793.8 | 2895.7 | -1.0 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.1 | 18164.0 | 17793.8 | 2895.7 | -1.0 | 1.020 | 1.020 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.3162 | 17488.0 | 17793.8 | 2895.7 | -0.5 | 0.987 | 0.983 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.3162 | 16544.0 | 17793.8 | 2895.7 | -0.5 | 0.945 | 0.930 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.3162 | 16398.0 | 17793.8 | 2895.7 | -0.5 | 0.939 | 0.922 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.3162 | 17588.0 | 17793.8 | 2895.7 | -0.5 | 0.991 | 0.988 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 1.0 | 10221.0 | 17793.8 | 2895.7 | 0.0 | 0.618 | 0.574 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 1.0 | 10271.0 | 17793.8 | 2895.7 | 0.0 | 0.622 | 0.577 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 1.0 | 9240.0 | 17793.8 | 2895.7 | 0.0 | 0.557 | 0.519 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 1.0 | 9431.0 | 17793.8 | 2895.7 | 0.0 | 0.570 | 0.530 | 2.619 | HCC1806 QL-XII-47 0 1 |