Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC1806 Torin1 2 72
0.001
 18344.0 18525.7 2822.7
-3.0
 0.993 0.990 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0032
 17594.0 18525.7 2822.7
-2.49
 0.962 0.950 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0032
 17394.0 18525.7 2822.7
-2.49
 0.954 0.939 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0032
 19127.0 18525.7 2822.7
-2.49
 1.020 1.030 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0032
 18056.0 18525.7 2822.7
-2.49
 0.981 0.975 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.01
 17484.0 18525.7 2822.7
-2.0
 0.958 0.944 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.01
 17680.0 18525.7 2822.7
-2.0
 0.966 0.954 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.01
 15496.0 18525.7 2822.7
-2.0
 0.873 0.836 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.01
 15576.0 18525.7 2822.7
-2.0
 0.876 0.841 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0316
 16078.0 18525.7 2822.7
-1.5
 0.898 0.868 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0316
 15602.0 18525.7 2822.7
-1.5
 0.877 0.842 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0316
 14982.0 18525.7 2822.7
-1.5
 0.850 0.809 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.0316
 16797.0 18525.7 2822.7
-1.5
 0.929 0.907 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.1
 12424.0 18525.7 2822.7
-1.0
 0.726 0.671 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.1
 12166.0 18525.7 2822.7
-1.0
 0.713 0.657 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.1
 11756.0 18525.7 2822.7
-1.0
 0.691 0.635 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.1
 11973.0 18525.7 2822.7
-1.0
 0.703 0.646 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.3162
 10029.0 18525.7 2822.7
-0.5
 0.595 0.541 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.3162
 9122.0 18525.7 2822.7
-0.5
 0.541 0.492 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.3162
 9239.0 18525.7 2822.7
-0.5
 0.548 0.499 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
0.3162
 9615.0 18525.7 2822.7
-0.5
 0.571 0.519 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
1.0
 7837.0 18525.7 2822.7
0.0
 0.457 0.423 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
1.0
 7733.0 18525.7 2822.7
0.0
 0.450 0.417 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
1.0
 8413.0 18525.7 2822.7
0.0
 0.495 0.454 2.714
HCC1806 Torin1 0 2
HCC1806 Torin1 2 72
1.0
 8176.0 18525.7 2822.7
0.0
 0.480 0.441 2.714
HCC1806 Torin1 0 2