Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0316 | 14326.0 | 14413.7 | 2222.1 | -1.5 | 0.995 | 0.994 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.0316 | 14428.0 | 14413.7 | 2222.1 | -1.5 | 1.000 | 1.000 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.1 | 14214.0 | 14413.7 | 2222.1 | -1.0 | 0.990 | 0.986 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.1 | 14448.0 | 14413.7 | 2222.1 | -1.0 | 1.000 | 1.000 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.1 | 15120.0 | 14413.7 | 2222.1 | -1.0 | 1.040 | 1.050 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.1 | 15194.0 | 14413.7 | 2222.1 | -1.0 | 1.040 | 1.050 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.3162 | 14458.0 | 14413.7 | 2222.1 | -0.5 | 1.000 | 1.000 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.3162 | 13707.0 | 14413.7 | 2222.1 | -0.5 | 0.963 | 0.951 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.3162 | 14748.0 | 14413.7 | 2222.1 | -0.5 | 1.020 | 1.020 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 0.3162 | 14429.0 | 14413.7 | 2222.1 | -0.5 | 1.000 | 1.000 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 1.0 | 12482.0 | 14413.7 | 2222.1 | 0.0 | 0.896 | 0.866 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 1.0 | 12359.0 | 14413.7 | 2222.1 | 0.0 | 0.889 | 0.857 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 1.0 | 12890.0 | 14413.7 | 2222.1 | 0.0 | 0.919 | 0.894 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 1.0 | 12353.0 | 14413.7 | 2222.1 | 0.0 | 0.889 | 0.857 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 3.1623 | 9022.0 | 14413.7 | 2222.1 | 0.5 | 0.681 | 0.626 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 3.1623 | 8295.0 | 14413.7 | 2222.1 | 0.5 | 0.630 | 0.575 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 3.1623 | 8465.0 | 14413.7 | 2222.1 | 0.5 | 0.642 | 0.587 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 3.1623 | 8830.0 | 14413.7 | 2222.1 | 0.5 | 0.668 | 0.613 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 10.0 | 4338.0 | 14413.7 | 2222.1 | 1.0 | 0.281 | 0.301 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 10.0 | 2258.0 | 14413.7 | 2222.1 | 1.0 | 0.006 | 0.157 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 10.0 | 4046.0 | 14413.7 | 2222.1 | 1.0 | 0.249 | 0.281 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-108 | 3 | 72 | 10.0 | 4482.0 | 14413.7 | 2222.1 | 1.0 | 0.297 | 0.311 | 2.697 | HCC1806 QL-XII-108 0 3 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.001 | 18408.0 | 17793.8 | 2895.7 | -3.0 | 1.030 | 1.030 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.001 | 18295.0 | 17793.8 | 2895.7 | -3.0 | 1.020 | 1.030 | 2.619 | HCC1806 QL-XII-47 0 1 |
| HCC1806 | QL-XII-47 | 1 | 72 | 0.001 | 18099.0 | 17793.8 | 2895.7 | -3.0 | 1.010 | 1.020 | 2.619 | HCC1806 QL-XII-47 0 1 |