Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | AZD8055 | 3 | 72 | 10.0 | 5621.0 | 14413.7 | 2222.1 | 1.0 | 0.411 | 0.390 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | AZD8055 | 3 | 72 | 10.0 | 5296.0 | 14413.7 | 2222.1 | 1.0 | 0.380 | 0.367 | 2.697 | HCC1806 AZD8055 0 3 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.001 | 17790.0 | 17793.8 | 2895.7 | -3.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.001 | 16767.0 | 17793.8 | 2895.7 | -3.0 | 0.955 | 0.942 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.001 | 17610.0 | 17793.8 | 2895.7 | -3.0 | 0.992 | 0.990 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.001 | 16767.0 | 17793.8 | 2895.7 | -3.0 | 0.955 | 0.942 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0032 | 17784.0 | 17793.8 | 2895.7 | -2.49 | 1.000 | 0.999 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0032 | 18605.0 | 17793.8 | 2895.7 | -2.49 | 1.030 | 1.050 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0032 | 17925.0 | 17793.8 | 2895.7 | -2.49 | 1.010 | 1.010 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0032 | 17715.0 | 17793.8 | 2895.7 | -2.49 | 0.997 | 0.996 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.01 | 17197.0 | 17793.8 | 2895.7 | -2.0 | 0.974 | 0.966 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.01 | 17212.0 | 17793.8 | 2895.7 | -2.0 | 0.975 | 0.967 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.01 | 16100.0 | 17793.8 | 2895.7 | -2.0 | 0.925 | 0.905 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.01 | 17804.0 | 17793.8 | 2895.7 | -2.0 | 1.000 | 1.000 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0316 | 16351.0 | 17793.8 | 2895.7 | -1.5 | 0.936 | 0.919 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0316 | 17297.0 | 17793.8 | 2895.7 | -1.5 | 0.978 | 0.972 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0316 | 16829.0 | 17793.8 | 2895.7 | -1.5 | 0.958 | 0.946 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.0316 | 17028.0 | 17793.8 | 2895.7 | -1.5 | 0.967 | 0.957 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.1 | 13496.0 | 17793.8 | 2895.7 | -1.0 | 0.800 | 0.758 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.1 | 12471.0 | 17793.8 | 2895.7 | -1.0 | 0.746 | 0.701 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.1 | 13637.0 | 17793.8 | 2895.7 | -1.0 | 0.807 | 0.766 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.1 | 13429.0 | 17793.8 | 2895.7 | -1.0 | 0.796 | 0.755 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.3162 | 8669.0 | 17793.8 | 2895.7 | -0.5 | 0.520 | 0.487 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.3162 | 8874.0 | 17793.8 | 2895.7 | -0.5 | 0.533 | 0.499 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 0.3162 | 9048.0 | 17793.8 | 2895.7 | -0.5 | 0.545 | 0.508 | 2.619 | HCC1806 QL-IV-100 0 1 |