Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC1806 | QL-IV-100 | 1 | 72 | 0.3162 | 9587.0 | 17793.8 | 2895.7 | -0.5 | 0.579 | 0.539 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 1.0 | 2098.0 | 17793.8 | 2895.7 | 0.0 | -0.116 | 0.118 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 1.0 | 2409.0 | 17793.8 | 2895.7 | 0.0 | -0.068 | 0.135 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 1.0 | 2103.0 | 17793.8 | 2895.7 | 0.0 | -0.115 | 0.118 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 1.0 | 2206.0 | 17793.8 | 2895.7 | 0.0 | -0.099 | 0.124 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1165.0 | 17793.8 | 2895.7 | 0.5 | -0.294 | 0.066 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1172.0 | 17793.8 | 2895.7 | 0.5 | -0.292 | 0.066 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1098.0 | 17793.8 | 2895.7 | 0.5 | -0.309 | 0.062 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 3.1623 | 1369.0 | 17793.8 | 2895.7 | 0.5 | -0.249 | 0.077 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1190.0 | 17793.8 | 2895.7 | 1.0 | -0.288 | 0.067 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1250.0 | 17793.8 | 2895.7 | 1.0 | -0.274 | 0.070 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1289.0 | 17793.8 | 2895.7 | 1.0 | -0.266 | 0.072 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 1 | 72 | 10.0 | 1392.0 | 17793.8 | 2895.7 | 1.0 | -0.244 | 0.078 | 2.619 | HCC1806 QL-IV-100 0 1 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.001 | 18167.0 | 18525.7 | 2822.7 | -3.0 | 0.986 | 0.981 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.001 | 18392.0 | 18525.7 | 2822.7 | -3.0 | 0.995 | 0.993 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.001 | 18295.0 | 18525.7 | 2822.7 | -3.0 | 0.991 | 0.988 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.001 | 18083.0 | 18525.7 | 2822.7 | -3.0 | 0.982 | 0.976 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0032 | 18598.0 | 18525.7 | 2822.7 | -2.49 | 1.000 | 1.000 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0032 | 19989.0 | 18525.7 | 2822.7 | -2.49 | 1.060 | 1.080 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0032 | 18742.0 | 18525.7 | 2822.7 | -2.49 | 1.010 | 1.010 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.0032 | 18220.0 | 18525.7 | 2822.7 | -2.49 | 0.988 | 0.984 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.01 | 18022.0 | 18525.7 | 2822.7 | -2.0 | 0.980 | 0.973 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.01 | 17432.0 | 18525.7 | 2822.7 | -2.0 | 0.956 | 0.941 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.01 | 17289.0 | 18525.7 | 2822.7 | -2.0 | 0.950 | 0.933 | 2.714 | HCC1806 QL-IV-100 0 2 |
| HCC1806 | QL-IV-100 | 2 | 72 | 0.01 | 17473.0 | 18525.7 | 2822.7 | -2.0 | 0.957 | 0.943 | 2.714 | HCC1806 QL-IV-100 0 2 |