Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1286.0 | 7167.9 | 2409.0 | 1.0 | -0.329 | 0.179 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 2 | 72 | 10.0 | 1162.0 | 7167.9 | 2409.0 | 1.0 | -0.371 | 0.162 | 1.573 | HCC70 Torin1 0 2 |
| HCC70 | Torin1 | 3 | 72 | 0.001 | 6234.0 | 6533.6 | 1943.1 | -3.0 | 0.947 | 0.954 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.001 | 6548.0 | 6533.6 | 1943.1 | -3.0 | 1.000 | 1.000 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.001 | 6690.0 | 6533.6 | 1943.1 | -3.0 | 1.030 | 1.020 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.001 | 6509.0 | 6533.6 | 1943.1 | -3.0 | 0.996 | 0.996 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.0032 | 5603.0 | 6533.6 | 1943.1 | -2.49 | 0.832 | 0.858 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.0032 | 6310.0 | 6533.6 | 1943.1 | -2.49 | 0.961 | 0.966 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.0032 | 6504.0 | 6533.6 | 1943.1 | -2.49 | 0.995 | 0.995 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.01 | 5724.0 | 6533.6 | 1943.1 | -2.0 | 0.854 | 0.876 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.01 | 5792.0 | 6533.6 | 1943.1 | -2.0 | 0.867 | 0.886 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.01 | 6042.0 | 6533.6 | 1943.1 | -2.0 | 0.913 | 0.925 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.01 | 5737.0 | 6533.6 | 1943.1 | -2.0 | 0.857 | 0.878 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.0316 | 4414.0 | 6533.6 | 1943.1 | -1.5 | 0.598 | 0.676 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.0316 | 4353.0 | 6533.6 | 1943.1 | -1.5 | 0.586 | 0.666 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.0316 | 3994.0 | 6533.6 | 1943.1 | -1.5 | 0.510 | 0.611 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.0316 | 4620.0 | 6533.6 | 1943.1 | -1.5 | 0.641 | 0.707 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.1 | 3354.0 | 6533.6 | 1943.1 | -1.0 | 0.366 | 0.513 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.1 | 3218.0 | 6533.6 | 1943.1 | -1.0 | 0.334 | 0.493 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.1 | 3680.0 | 6533.6 | 1943.1 | -1.0 | 0.441 | 0.563 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.1 | 3196.0 | 6533.6 | 1943.1 | -1.0 | 0.329 | 0.489 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.3162 | 2735.0 | 6533.6 | 1943.1 | -0.5 | 0.216 | 0.419 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.3162 | 2849.0 | 6533.6 | 1943.1 | -0.5 | 0.245 | 0.436 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.3162 | 2790.0 | 6533.6 | 1943.1 | -0.5 | 0.230 | 0.427 | 1.750 | HCC70 Torin1 0 3 |
| HCC70 | Torin1 | 3 | 72 | 0.3162 | 3050.0 | 6533.6 | 1943.1 | -0.5 | 0.294 | 0.467 | 1.750 | HCC70 Torin1 0 3 |