Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-47 | 3 | 72 | 0.0316 | 6490.0 | 6533.6 | 1943.1 | -1.5 | 0.992 | 0.993 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0316 | 6798.0 | 6533.6 | 1943.1 | -1.5 | 1.050 | 1.040 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.1 | 5932.0 | 6533.6 | 1943.1 | -1.0 | 0.893 | 0.908 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.1 | 6567.0 | 6533.6 | 1943.1 | -1.0 | 1.010 | 1.010 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.1 | 6777.0 | 6533.6 | 1943.1 | -1.0 | 1.040 | 1.040 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.1 | 6261.0 | 6533.6 | 1943.1 | -1.0 | 0.952 | 0.958 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.3162 | 5938.0 | 6533.6 | 1943.1 | -0.5 | 0.894 | 0.909 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.3162 | 5389.0 | 6533.6 | 1943.1 | -0.5 | 0.792 | 0.825 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.3162 | 5553.0 | 6533.6 | 1943.1 | -0.5 | 0.822 | 0.850 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.3162 | 6003.0 | 6533.6 | 1943.1 | -0.5 | 0.905 | 0.919 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 1.0 | 2529.0 | 6533.6 | 1943.1 | 0.0 | 0.163 | 0.387 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 1.0 | 2517.0 | 6533.6 | 1943.1 | 0.0 | 0.159 | 0.385 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 1.0 | 2208.0 | 6533.6 | 1943.1 | 0.0 | 0.076 | 0.338 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 1.0 | 2447.0 | 6533.6 | 1943.1 | 0.0 | 0.141 | 0.375 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 3.1623 | 258.0 | 6533.6 | 1943.1 | 0.5 | -0.685 | 0.040 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 3.1623 | 318.0 | 6533.6 | 1943.1 | 0.5 | -0.645 | 0.049 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 3.1623 | 254.0 | 6533.6 | 1943.1 | 0.5 | -0.687 | 0.039 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 3.1623 | 274.0 | 6533.6 | 1943.1 | 0.5 | -0.674 | 0.042 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 10.0 | 383.0 | 6533.6 | 1943.1 | 1.0 | -0.605 | 0.059 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 10.0 | 256.0 | 6533.6 | 1943.1 | 1.0 | -0.686 | 0.039 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 10.0 | 192.0 | 6533.6 | 1943.1 | 1.0 | -0.734 | 0.029 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 10.0 | 235.0 | 6533.6 | 1943.1 | 1.0 | -0.701 | 0.036 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.001 | 7560.0 | 7580.8 | 2503.8 | -3.0 | 0.997 | 0.997 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.001 | 7220.0 | 7580.8 | 2503.8 | -3.0 | 0.940 | 0.952 | 1.598 | HCC70 QL-XII-61 0 1 |
| HCC70 | QL-XII-61 | 1 | 72 | 0.001 | 7561.0 | 7580.8 | 2503.8 | -3.0 | 0.997 | 0.997 | 1.598 | HCC70 QL-XII-61 0 1 |