Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3810.0 | 7580.8 | 2503.8 | -1.5 | 0.300 | 0.503 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3496.0 | 7580.8 | 2503.8 | -1.5 | 0.232 | 0.461 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.0316 | 3993.0 | 7580.8 | 2503.8 | -1.5 | 0.339 | 0.527 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2596.0 | 7580.8 | 2503.8 | -1.0 | 0.023 | 0.342 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2487.0 | 7580.8 | 2503.8 | -1.0 | -0.004 | 0.328 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2576.0 | 7580.8 | 2503.8 | -1.0 | 0.018 | 0.340 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.1 | 2732.0 | 7580.8 | 2503.8 | -1.0 | 0.056 | 0.360 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 901.0 | 7580.8 | 2503.8 | -0.5 | -0.472 | 0.119 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 848.0 | 7580.8 | 2503.8 | -0.5 | -0.492 | 0.112 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1092.0 | 7580.8 | 2503.8 | -0.5 | -0.405 | 0.144 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 0.3162 | 1002.0 | 7580.8 | 2503.8 | -0.5 | -0.436 | 0.132 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 265.0 | 7580.8 | 2503.8 | 0.0 | -0.755 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 263.0 | 7580.8 | 2503.8 | 0.0 | -0.756 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 268.0 | 7580.8 | 2503.8 | 0.0 | -0.753 | 0.035 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 1.0 | 314.0 | 7580.8 | 2503.8 | 0.0 | -0.727 | 0.041 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 49.0 | 7580.8 | 2503.8 | 0.5 | -0.915 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 46.0 | 7580.8 | 2503.8 | 0.5 | -0.918 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 43.0 | 7580.8 | 2503.8 | 0.5 | -0.921 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 3.1623 | 52.0 | 7580.8 | 2503.8 | 0.5 | -0.911 | 0.007 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 10.0 | 44.0 | 7580.8 | 2503.8 | 1.0 | -0.920 | 0.006 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 10.0 | 21.0 | 7580.8 | 2503.8 | 1.0 | -0.950 | 0.003 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 10.0 | 10.0 | 7580.8 | 2503.8 | 1.0 | -0.968 | 0.001 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 1 | 72 | 10.0 | 23.0 | 7580.8 | 2503.8 | 1.0 | -0.947 | 0.003 | 1.598 | HCC70 Torin2 0 1 |
| HCC70 | Torin2 | 2 | 72 | 0.001 | 7033.0 | 7167.9 | 2409.0 | -3.0 | 0.976 | 0.981 | 1.573 | HCC70 Torin2 0 2 |
| HCC70 | Torin2 | 2 | 72 | 0.001 | 5960.0 | 7167.9 | 2409.0 | -3.0 | 0.779 | 0.831 | 1.573 | HCC70 Torin2 0 2 |