Evaluation of the sensitivity of two triple-negative breast cancer cell lines (HCC1806, HCC70) to a collection of dual mTOR and PI3K-like kinase (PIKK) inhibitors. Dataset 1 of 2: GR values. - Dataset (ID:20366)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC70 | QL-XII-47 | 2 | 72 | 1.0 | 3175.0 | 7167.9 | 2409.0 | 0.0 | 0.192 | 0.443 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 1.0 | 2930.0 | 7167.9 | 2409.0 | 0.0 | 0.133 | 0.409 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 1.0 | 3337.0 | 7167.9 | 2409.0 | 0.0 | 0.230 | 0.466 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 3.1623 | 526.0 | 7167.9 | 2409.0 | 0.5 | -0.620 | 0.073 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 3.1623 | 372.0 | 7167.9 | 2409.0 | 0.5 | -0.695 | 0.052 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 3.1623 | 393.0 | 7167.9 | 2409.0 | 0.5 | -0.684 | 0.055 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 3.1623 | 438.0 | 7167.9 | 2409.0 | 0.5 | -0.662 | 0.061 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 163.0 | 7167.9 | 2409.0 | 1.0 | -0.820 | 0.023 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 177.0 | 7167.9 | 2409.0 | 1.0 | -0.810 | 0.025 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 163.0 | 7167.9 | 2409.0 | 1.0 | -0.820 | 0.023 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 2 | 72 | 10.0 | 159.0 | 7167.9 | 2409.0 | 1.0 | -0.822 | 0.022 | 1.573 | HCC70 QL-XII-47 0 2 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.001 | 6411.0 | 6533.6 | 1943.1 | -3.0 | 0.978 | 0.981 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.001 | 6163.0 | 6533.6 | 1943.1 | -3.0 | 0.934 | 0.943 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.001 | 6706.0 | 6533.6 | 1943.1 | -3.0 | 1.030 | 1.030 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.001 | 5853.0 | 6533.6 | 1943.1 | -3.0 | 0.878 | 0.896 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0032 | 6417.0 | 6533.6 | 1943.1 | -2.49 | 0.980 | 0.982 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0032 | 6784.0 | 6533.6 | 1943.1 | -2.49 | 1.040 | 1.040 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0032 | 6601.0 | 6533.6 | 1943.1 | -2.49 | 1.010 | 1.010 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0032 | 6711.0 | 6533.6 | 1943.1 | -2.49 | 1.030 | 1.030 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.01 | 5974.0 | 6533.6 | 1943.1 | -2.0 | 0.900 | 0.914 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.01 | 5982.0 | 6533.6 | 1943.1 | -2.0 | 0.902 | 0.916 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.01 | 6171.0 | 6533.6 | 1943.1 | -2.0 | 0.936 | 0.944 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.01 | 6407.0 | 6533.6 | 1943.1 | -2.0 | 0.978 | 0.981 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0316 | 6103.0 | 6533.6 | 1943.1 | -1.5 | 0.924 | 0.934 | 1.750 | HCC70 QL-XII-47 0 3 |
| HCC70 | QL-XII-47 | 3 | 72 | 0.0316 | 6168.0 | 6533.6 | 1943.1 | -1.5 | 0.935 | 0.944 | 1.750 | HCC70 QL-XII-47 0 3 |