Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

 Full screen view
Filter results: >>>>
Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
BT-549 MK2206 2 72
0.032
 4657.3 4569.8 1249.6
-1.49
 1.020 1.020 1.871
BT549 MK2206 0 2 72
BT-549 MK2206 2 72
0.1
 4437.0 4569.8 1249.6
-1.0
 0.969 0.971 1.871
BT549 MK2206 0 2 72
BT-549 MK2206 2 72
0.32
 4220.0 4569.8 1249.6
-0.495
 0.917 0.923 1.871
BT549 MK2206 0 2 72
BT-549 MK2206 2 72
1.0
 5246.0 4569.8 1249.6
0.0
 1.150 1.150 1.871
BT549 MK2206 0 2 72
BT-549 MK2206 2 72
3.2
 6181.5 4569.8 1249.6
0.505
 1.350 1.350 1.871
BT549 MK2206 0 2 72
BT-549 PI103 2 72
0.001
 4459.5 4640.0 1249.6
-3.0
 0.959 0.961 1.893
BT549 PI103 0 2 72
BT-549 PI103 2 72
0.0032
 4553.5 4640.0 1249.6
-2.49
 0.980 0.981 1.893
BT549 PI103 0 2 72
BT-549 PI103 2 72
0.01
 4455.5 4640.0 1249.6
-2.0
 0.958 0.960 1.893
BT549 PI103 0 2 72
BT-549 PI103 2 72
0.032
 4290.3 4640.0 1249.6
-1.49
 0.919 0.925 1.893
BT549 PI103 0 2 72
BT-549 PI103 2 72
0.1
 3376.8 4640.0 1249.6
-1.0
 0.691 0.728 1.893
BT549 PI103 0 2 72
BT-549 PI103 2 72
0.32
 2319.3 4640.0 1249.6
-0.495
 0.386 0.500 1.893
BT549 PI103 0 2 72
BT-549 PI103 2 72
1.0
 1673.8 4640.0 1249.6
0.0
 0.167 0.361 1.893
BT549 PI103 0 2 72
BT-549 PI103 2 72
3.2
 1297.5 4640.0 1249.6
0.505
 0.020 0.280 1.893
BT549 PI103 0 2 72
BT-549 PIK-93 2 72
0.001
 4719.3 4941.3 1249.6
-3.0
 0.954 0.955 1.983
BT549 PIK93 0 2 72
BT-549 PIK-93 2 72
0.0032
 4823.8 4941.3 1249.6
-2.49
 0.976 0.976 1.983
BT549 PIK93 0 2 72
BT-549 PIK-93 2 72
0.01
 4859.0 4941.3 1249.6
-2.0
 0.983 0.983 1.983
BT549 PIK93 0 2 72
BT-549 PIK-93 2 72
0.032
 4906.5 4941.3 1249.6
-1.49
 0.993 0.993 1.983
BT549 PIK93 0 2 72
BT-549 PIK-93 2 72
0.1
 4882.3 4941.3 1249.6
-1.0
 0.988 0.988 1.983
BT549 PIK93 0 2 72
BT-549 PIK-93 2 72
0.32
 4561.0 4941.3 1249.6
-0.495
 0.921 0.923 1.983
BT549 PIK93 0 2 72
BT-549 PIK-93 2 72
1.0
 4329.3 4941.3 1249.6
0.0
 0.871 0.876 1.983
BT549 PIK93 0 2 72
BT-549 PIK-93 2 72
3.2
 3525.5 4941.3 1249.6
0.505
 0.687 0.713 1.983
BT549 PIK93 0 2 72
BT-549 Sirolimus 2 72
0.001
 3236.3 4441.5 1249.6
-3.0
 0.682 0.729 1.830
BT549 Rapamycin 0 2 72
BT-549 Sirolimus 2 72
0.0032
 2951.0 4441.5 1249.6
-2.49
 0.599 0.664 1.830
BT549 Rapamycin 0 2 72
BT-549 Sirolimus 2 72
0.01
 3116.8 4441.5 1249.6
-2.0
 0.648 0.702 1.830
BT549 Rapamycin 0 2 72
BT-549 Sirolimus 2 72
0.032
 3021.3 4441.5 1249.6
-1.49
 0.620 0.680 1.830
BT549 Rapamycin 0 2 72