Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)
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| Cell line | Drug name | Experimental replicate | Timepoint | Drug concentration | Live cell count | Average live cell count, DMSO control | Average live cell count (time = 0) | Log10(drug concentration) | GR value | Relative cell count (treatment versus DMSO) | Cell doublings (DMSO control) | Experiment name |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | CAL-101 | 3 | 72 | 0.32 | 4090.8 | 4189.5 | 571.3 | -0.495 | 0.983 | 0.976 | 2.874 | Hs578T CAL101 3 |
| Hs 578T | CAL-101 | 3 | 72 | 1.0 | 3764.0 | 4189.5 | 571.3 | 0.0 | 0.927 | 0.898 | 2.874 | Hs578T CAL101 3 |
| Hs 578T | CAL-101 | 3 | 72 | 3.2 | 3370.5 | 4189.5 | 571.3 | 0.505 | 0.854 | 0.805 | 2.874 | Hs578T CAL101 3 |
| Hs 578T | Everolimus | 3 | 72 | 0.001 | 2787.3 | 4114.8 | 571.3 | -3.0 | 0.744 | 0.677 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Everolimus | 3 | 72 | 0.0032 | 2581.5 | 4114.8 | 571.3 | -2.49 | 0.698 | 0.627 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Everolimus | 3 | 72 | 0.01 | 2655.0 | 4114.8 | 571.3 | -2.0 | 0.715 | 0.645 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Everolimus | 3 | 72 | 0.032 | 2575.5 | 4114.8 | 571.3 | -1.49 | 0.697 | 0.626 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Everolimus | 3 | 72 | 0.1 | 2632.0 | 4114.8 | 571.3 | -1.0 | 0.710 | 0.640 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Everolimus | 3 | 72 | 0.32 | 2601.3 | 4114.8 | 571.3 | -0.495 | 0.703 | 0.632 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Everolimus | 3 | 72 | 1.0 | 2521.3 | 4114.8 | 571.3 | 0.0 | 0.684 | 0.613 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Everolimus | 3 | 72 | 3.2 | 2434.8 | 4114.8 | 571.3 | 0.505 | 0.664 | 0.592 | 2.848 | Hs578T Everolimus 3 |
| Hs 578T | Pictilisib | 3 | 72 | 0.001 | 4322.0 | 4297.8 | 571.3 | -3.0 | 1.000 | 1.010 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | Pictilisib | 3 | 72 | 0.0032 | 4327.5 | 4297.8 | 571.3 | -2.49 | 1.000 | 1.010 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | Pictilisib | 3 | 72 | 0.01 | 4244.3 | 4297.8 | 571.3 | -2.0 | 0.991 | 0.988 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | Pictilisib | 3 | 72 | 0.032 | 3958.0 | 4297.8 | 571.3 | -1.49 | 0.944 | 0.921 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | Pictilisib | 3 | 72 | 0.1 | 3381.8 | 4297.8 | 571.3 | -1.0 | 0.842 | 0.787 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | Pictilisib | 3 | 72 | 0.32 | 2732.8 | 4297.8 | 571.3 | -0.495 | 0.712 | 0.636 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | Pictilisib | 3 | 72 | 1.0 | 2218.8 | 4297.8 | 571.3 | 0.0 | 0.594 | 0.516 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | Pictilisib | 3 | 72 | 3.2 | 1756.3 | 4297.8 | 571.3 | 0.505 | 0.471 | 0.409 | 2.911 | Hs578T GDC0941 3 |
| Hs 578T | GDC-0980 | 3 | 72 | 0.001 | 4093.0 | 4064.8 | 571.3 | -3.0 | 1.000 | 1.010 | 2.831 | Hs578T GDC0980 3 |
| Hs 578T | GDC-0980 | 3 | 72 | 0.0032 | 3967.0 | 4064.8 | 571.3 | -2.49 | 0.983 | 0.976 | 2.831 | Hs578T GDC0980 3 |
| Hs 578T | GDC-0980 | 3 | 72 | 0.01 | 3823.0 | 4064.8 | 571.3 | -2.0 | 0.957 | 0.941 | 2.831 | Hs578T GDC0980 3 |
| Hs 578T | GDC-0980 | 3 | 72 | 0.032 | 3448.8 | 4064.8 | 571.3 | -1.49 | 0.887 | 0.848 | 2.831 | Hs578T GDC0980 3 |
| Hs 578T | GDC-0980 | 3 | 72 | 0.1 | 2533.8 | 4064.8 | 571.3 | -1.0 | 0.692 | 0.623 | 2.831 | Hs578T GDC0980 3 |
| Hs 578T | GDC-0980 | 3 | 72 | 0.32 | 1561.3 | 4064.8 | 571.3 | -0.495 | 0.426 | 0.384 | 2.831 | Hs578T GDC0980 3 |