Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

 Full screen view
Filter results: >>>>
Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC38 CAL-101 2 72
0.001
 3075.8 3073.0 690.5
-3.0
 1.000 1.000 2.154
HCC38 CAL101 0 2 72
HCC38 CAL-101 2 72
0.0032
 3088.8 3073.0 690.5
-2.49
 1.000 1.010 2.154
HCC38 CAL101 0 2 72
HCC38 CAL-101 2 72
0.01
 2962.3 3073.0 690.5
-2.0
 0.966 0.964 2.154
HCC38 CAL101 0 2 72
HCC38 CAL-101 2 72
0.032
 3149.8 3073.0 690.5
-1.49
 1.020 1.020 2.154
HCC38 CAL101 0 2 72
HCC38 CAL-101 2 72
0.1
 3062.0 3073.0 690.5
-1.0
 0.997 0.996 2.154
HCC38 CAL101 0 2 72
HCC38 CAL-101 2 72
0.32
 3061.5 3073.0 690.5
-0.495
 0.997 0.996 2.154
HCC38 CAL101 0 2 72
HCC38 CAL-101 2 72
1.0
 2843.0 3073.0 690.5
0.0
 0.929 0.925 2.154
HCC38 CAL101 0 2 72
HCC38 CAL-101 2 72
3.2
 2692.3 3073.0 690.5
0.505
 0.881 0.876 2.154
HCC38 CAL101 0 2 72
HCC38 Everolimus 2 72
0.001
 2094.3 3106.8 690.5
-3.0
 0.668 0.674 2.170
HCC38 Everolimus 0 2 72
HCC38 Everolimus 2 72
0.0032
 2022.0 3106.8 690.5
-2.49
 0.641 0.651 2.170
HCC38 Everolimus 0 2 72
HCC38 Everolimus 2 72
0.01
 2005.0 3106.8 690.5
-2.0
 0.634 0.645 2.170
HCC38 Everolimus 0 2 72
HCC38 Everolimus 2 72
0.032
 1979.3 3106.8 690.5
-1.49
 0.625 0.637 2.170
HCC38 Everolimus 0 2 72
HCC38 Everolimus 2 72
0.1
 1997.8 3106.8 690.5
-1.0
 0.632 0.643 2.170
HCC38 Everolimus 0 2 72
HCC38 Everolimus 2 72
0.32
 1974.8 3106.8 690.5
-0.495
 0.623 0.636 2.170
HCC38 Everolimus 0 2 72
HCC38 Everolimus 2 72
1.0
 1894.0 3106.8 690.5
0.0
 0.592 0.610 2.170
HCC38 Everolimus 0 2 72
HCC38 Everolimus 2 72
3.2
 1863.8 3106.8 690.5
0.505
 0.580 0.600 2.170
HCC38 Everolimus 0 2 72
HCC38 Pictilisib 2 72
0.001
 2725.8 2985.8 690.5
-3.0
 0.916 0.913 2.112
HCC38 GDC0941 0 2 72
HCC38 Pictilisib 2 72
0.0032
 3120.5 2985.8 690.5
-2.49
 1.040 1.050 2.112
HCC38 GDC0941 0 2 72
HCC38 Pictilisib 2 72
0.01
 2991.8 2985.8 690.5
-2.0
 1.000 1.000 2.112
HCC38 GDC0941 0 2 72
HCC38 Pictilisib 2 72
0.032
 3075.0 2985.8 690.5
-1.49
 1.030 1.030 2.112
HCC38 GDC0941 0 2 72
HCC38 Pictilisib 2 72
0.1
 2874.3 2985.8 690.5
-1.0
 0.964 0.963 2.112
HCC38 GDC0941 0 2 72
HCC38 Pictilisib 2 72
0.32
 2593.8 2985.8 690.5
-0.495
 0.871 0.869 2.112
HCC38 GDC0941 0 2 72
HCC38 Pictilisib 2 72
1.0
 2220.5 2985.8 690.5
0.0
 0.738 0.744 2.112
HCC38 GDC0941 0 2 72
HCC38 Pictilisib 2 72
3.2
 1918.0 2985.8 690.5
0.505
 0.622 0.642 2.112
HCC38 GDC0941 0 2 72
HCC38 GDC-0980 2 72
0.001
 3094.3 3084.3 690.5
-3.0
 1.000 1.000 2.159
HCC38 GDC0980 0 2 72