Evaluation of the sensitivities of six triple-negative breast cancer (TNBC) cell lines to 23 different PI3K/AKT/mTOR inhibitors or to a MEK inhibitor (trametinib). Dataset 1 of 2: GR values. - Dataset (ID:20364)

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Cell line Drug name Experimental replicate Timepoint Drug concentration Live cell count Average live cell count, DMSO control Average live cell count (time = 0) Log10(drug concentration) GR value Relative cell count (treatment versus DMSO) Cell doublings (DMSO control) Experiment name
HCC38 GDC-0980 2 72
0.0032
 3061.0 3084.3 690.5
-2.49
 0.993 0.992 2.159
HCC38 GDC0980 0 2 72
HCC38 GDC-0980 2 72
0.01
 3051.0 3084.3 690.5
-2.0
 0.990 0.989 2.159
HCC38 GDC0980 0 2 72
HCC38 GDC-0980 2 72
0.032
 2855.5 3084.3 690.5
-1.49
 0.930 0.926 2.159
HCC38 GDC0980 0 2 72
HCC38 GDC-0980 2 72
0.1
 2255.3 3084.3 690.5
-1.0
 0.730 0.731 2.159
HCC38 GDC0980 0 2 72
HCC38 GDC-0980 2 72
0.32
 1610.5 3084.3 690.5
-0.495
 0.480 0.522 2.159
HCC38 GDC0980 0 2 72
HCC38 GDC-0980 2 72
1.0
 1316.5 3084.3 690.5
0.0
 0.348 0.427 2.159
HCC38 GDC0980 0 2 72
HCC38 GDC-0980 2 72
3.2
 938.5 3084.3 690.5
0.505
 0.153 0.304 2.159
HCC38 GDC0980 0 2 72
HCC38 Omipalisib 2 72
0.001
 2372.8 3009.3 690.5
-3.0
 0.788 0.788 2.124
HCC38 GSK458 0 2 72
HCC38 Omipalisib 2 72
0.0032
 2817.3 3009.3 690.5
-2.49
 0.939 0.936 2.124
HCC38 GSK458 0 2 72
HCC38 Omipalisib 2 72
0.01
 2084.3 3009.3 690.5
-2.0
 0.682 0.693 2.124
HCC38 GSK458 0 2 72
HCC38 Omipalisib 2 72
0.032
 1659.5 3009.3 690.5
-1.49
 0.511 0.551 2.124
HCC38 GSK458 0 2 72
HCC38 Omipalisib 2 72
0.1
 1213.3 3009.3 690.5
-1.0
 0.304 0.403 2.124
HCC38 GSK458 0 2 72
HCC38 Omipalisib 2 72
0.32
 814.8 3009.3 690.5
-0.495
 0.081 0.271 2.124
HCC38 GSK458 0 2 72
HCC38 Omipalisib 2 72
1.0
 538.3 3009.3 690.5
0.0
 -0.111 0.179 2.124
HCC38 GSK458 0 2 72
HCC38 Omipalisib 2 72
3.2
 179.0 3009.3 690.5
0.505
 -0.470 0.060 2.124
HCC38 GSK458 0 2 72
HCC38 KIN001-244 2 72
0.001
 3129.0 3196.0 690.5
-3.0
 0.981 0.979 2.210
HCC38 KIN001-244 0 2 72
HCC38 KIN001-244 2 72
0.0032
 3018.0 3196.0 690.5
-2.49
 0.949 0.944 2.210
HCC38 KIN001-244 0 2 72
HCC38 KIN001-244 2 72
0.01
 3065.8 3196.0 690.5
-2.0
 0.963 0.959 2.210
HCC38 KIN001-244 0 2 72
HCC38 KIN001-244 2 72
0.032
 3064.3 3196.0 690.5
-1.49
 0.962 0.959 2.210
HCC38 KIN001-244 0 2 72
HCC38 KIN001-244 2 72
0.1
 3190.3 3196.0 690.5
-1.0
 0.998 0.998 2.210
HCC38 KIN001-244 0 2 72
HCC38 KIN001-244 2 72
0.32
 3080.5 3196.0 690.5
-0.495
 0.967 0.964 2.210
HCC38 KIN001-244 0 2 72
HCC38 KIN001-244 2 72
1.0
 3137.5 3196.0 690.5
0.0
 0.983 0.982 2.210
HCC38 KIN001-244 0 2 72
HCC38 KIN001-244 2 72
3.2
 3015.5 3196.0 690.5
0.505
 0.948 0.944 2.210
HCC38 KIN001-244 0 2 72
HCC38 MK2206 2 72
0.001
 3051.8 3083.8 690.5
-3.0
 0.990 0.990 2.159
HCC38 MK2206 0 2 72
HCC38 MK2206 2 72
0.0032
 3013.8 3083.8 690.5
-2.49
 0.979 0.977 2.159
HCC38 MK2206 0 2 72